RECRUITING

Study of Oral Fluid Testing Approach

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to identify and evaluate oral fluid testing as a biologic measure of cannabis use days that can be assessed remotely. The researchers will conduct this fully virtual study among a community sample of 200 individuals aged 18-30 years who have used cannabis at least 1 time per week on average in the past 30 days. Participants will complete oral fluid (saliva) tests, urine tests, and Timeline Follow-back interviews (self-report) that indicate their recent cannabis use (delta-9-THC). Participants will present for 3 virtual study visits and be asked to complete activities in between: Study Visit 1 (Day 0; informed consent, baseline survey, TLFB interview), Study Visit 2 (\~Day 3; TLFB interview, urine testing), 6 days of at-home videorecorded oral fluid testing, Study Visit 3 (\~Day 12; TLFB interview, urine test, oral fluid test, survey, interview).

Official Title

Oral Fluid Testing to Assess Cannabis Non-Use in Remote Clinical Trials

Quick Facts

Study Start:2025-10-27
Study Completion:2027-05
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06891235

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 30 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age 18 to 30 years
  2. * Cannabis use on \>=1x/week in the past 30 days
  3. * Ownership of a portable device that is capable of videoconference and videorecording (i.e., smartphone, tablet computer, or laptop computer)
  4. * Ability to read and speak English
  5. * Availability for duration of the study (2-3 weeks).
  6. * To proceed to oral fluid testing, positive result for urinary TCH-COOH
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Lydia A Shrier, MD, MPH
CONTACT
(617) 355-8306
lydia.shrier@childrens.harvard.edu
Sion K Harris, PhD, RN
CONTACT
857-218-4304
sion.harris@childrens.harvard.edu

Study Locations (Sites)

Boston Children's Hospital
Boston, Massachusetts, 02115
United States

Collaborators and Investigators

Sponsor: Boston Children's Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-10-27
Study Completion Date2027-05

Study Record Updates

Study Start Date2025-10-27
Study Completion Date2027-05

Terms related to this study

Keywords Provided by Researchers

  • cannabis use
  • young adult
  • oral fluid testing

Additional Relevant MeSH Terms

  • Cannabis Use
  • Cannabis Intoxication
  • Cannabis Use Disorder