Circadian Rhythms in Human Adipose

Description

The goal of this study is to understand the underlying circadian rhythms in subcutaneous adipose tissue of humans with our without continuous feeding and how these are altered in people who have obesity.

Conditions

Obesity, Abdominal, Feeding Patterns

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Study Overview

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Study Details

Study overview

The goal of this study is to understand the underlying circadian rhythms in subcutaneous adipose tissue of humans with our without continuous feeding and how these are altered in people who have obesity.

Circadian Regulation of Human Adipose Tissue Metabolism

Circadian Rhythms in Human Adipose

Condition
Obesity, Abdominal
Intervention / Treatment

-

Contacts and Locations

Rochester

Mayo Clinic, Rochester, Minnesota, United States, 55901

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * BMI 20-25 kg/m2 or 30-37 kg/m2
  • * For participants with obesity a waist-to-hip ratio of ≥0.95 in males and ≥0.90 in females.
  • * sedentary
  • * females: non pregnant or breastfeeding
  • * ability to provide written informed consent and follow study instructions
  • * History of mediations that impact adipocyte/lipid metabolism
  • * smoking
  • * insomnia
  • * sleep apnea
  • * sleep medication use
  • * employment in night or shift work
  • * extreme chronotypes
  • * Allergy to lidocaine

Ages Eligible for Study

18 Years to 55 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Mayo Clinic,

Study Record Dates

2030-12