NOT_YET_RECRUITING

Enhancing Reading Recovery in Aphasia with TDCS and Phonomotor Therapy

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study is designed for individuals with aphasia, a language disorder that affects many stroke survivors, making it difficult to read, speak, and understand language. Up to 70% of people with aphasia struggle with reading, which impacts their ability to communicate, work, and engage in daily life. The study aims to test a new approach to reading rehabilitation by combining Phono-Motor Treatment (PMT), a language therapy adapted to improve reading, with transcranial direct current stimulation (tDCS), a safe and painless brain stimulation technique. tDCS delivers a mild electrical current to the brain, which may enhance learning. This study will assess whether adding tDCS to PMT improves reading therapy outcomes.

Official Title

Enhancing Reading Recovery in Aphasia with TDCS and PMT

Quick Facts

Study Start:2025-05-01
Study Completion:2026-02-14
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:NOT_YET_RECRUITING

Study ID

NCT06891638

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 80 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Chronic (\>6 months) left-hemisphere stroke
  2. * Aphasia diagnosis.
  3. * Deficits in reading aloud.
  1. * Eye condition not correctable with lenses and interfering with reading (e.g., blindness)
  2. * Severe apraxia of speech or cognitive deficits preventing participation.
  3. * Participation in one-on-one aphasia rehabilitation during the study period.
  4. * Brain disorders other than stroke (such as Alzheimer's Disease or Dementia, Parkinson's Disease, etc)
  5. * Contraindications of tDCS or MRI
  6. * Skin condition affecting the scull (e.g., psoriasis) or open wounds at the stimulation site.
  7. * Presence of metallic implants (e.g., cardiac stimulators or pacemakers, cochlear implants)
  8. * History of ongoing/unmanaged seizers
  9. * Pregnancy
  10. * Claustrophobia
  11. * Inability to lie flat on the back

Contacts and Locations

Study Contact

Olga Boukrina, Ph.D.
CONTACT
973-324-3587
oboukrina@kesslerfoundation.org

Study Locations (Sites)

Kessler Foundation
West Orange, New Jersey, 07052
United States
Medical College of Wisconsin
Milwaukee, Wisconsin, 53226
United States

Collaborators and Investigators

Sponsor: Kessler Foundation

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-05-01
Study Completion Date2026-02-14

Study Record Updates

Study Start Date2025-05-01
Study Completion Date2026-02-14

Terms related to this study

Keywords Provided by Researchers

  • Aphasia
  • Post-stroke rehabilitation
  • Reading impairment
  • Language therapy
  • Transcranial Direct Current Stimulation (tDCS)
  • Phonomotor Treatment (PMT)
  • Brain stimulation therapy
  • Neurorehabilitation
  • Randomized controlled trial (RCT)
  • Non-invasive brain stimulation
  • Neuromodulation
  • Speech and language therapy

Additional Relevant MeSH Terms

  • Stroke
  • Aphasia