RECRUITING

Diffusion MRI for Quantitative Assessment of Myofascial Pain

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to assess the diagnostic accuracy of diffusion MRI for evaluation of the jaw muscles for patients with masticatory myofascial pain syndrome.

Official Title

Development of RPBM for Quantitative Assessment of Myofascial Pain

Quick Facts

Study Start:2025-09-04

Study Completion:2026-07

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT06892041

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:Yes

Standard Ages:ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
* Men and women 18-65 years of age * Ability to give informed consent * Symptoms meeting criteria for normal or latent/active temporomandibular myofascial pain	* Contraindications to MRI scanning including severe obesity or difficulty in laying in a supine position, intracranial clips, metal implants, external metallic devices/objects/clips within 10mm of the head, suspected or confirmed metal in the eyes (history of welding or similar activity), claustrophobia, cardiac pacemaker or pacing wires * Pregnancy or breast feeding * Traumatic injury of masticatory muscles or temporomandibular joint within last 12 months * Mandibular fracture within last 12 months * Initiation of additional treatment of myofascial pain within the past 1 month * Received masseter Botox within the last 4 months

Inclusion Criteria

Exclusion Criteria

* Men and women 18-65 years of age
* Ability to give informed consent
* Symptoms meeting criteria for normal or latent/active temporomandibular myofascial pain

* Contraindications to MRI scanning including severe obesity or difficulty in laying in a supine position, intracranial clips, metal implants, external metallic devices/objects/clips within 10mm of the head, suspected or confirmed metal in the eyes (history of welding or similar activity), claustrophobia, cardiac pacemaker or pacing wires
* Pregnancy or breast feeding
* Traumatic injury of masticatory muscles or temporomandibular joint within last 12 months
* Mandibular fracture within last 12 months
* Initiation of additional treatment of myofascial pain within the past 1 month
* Received masseter Botox within the last 4 months

Contacts and Locations

Study Contact

Elizabeth Lane

CONTACT

646-962-8394

ell2032@med.cornell.edu

Principal Investigator

Gene Kim, PhD

PRINCIPAL_INVESTIGATOR

Weill Medical College of Cornell University

Study Locations (Sites)

New York University

New York, New York, 10016

United States

Weill Cornell Medicine

New York, New York, 10065

United States

Collaborators and Investigators

Sponsor: Weill Medical College of Cornell University

Gene Kim, PhD, PRINCIPAL_INVESTIGATOR, Weill Medical College of Cornell University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-09-04

Study Completion Date2026-07

Study Record Updates

Study Start Date2025-09-04

Study Completion Date2026-07

Terms related to this study

Additional Relevant MeSH Terms

Masticatory Myofascial Pain Syndrome