RECRUITING

Acupuncture for People Experiencing Period Loss Due to Chemotherapy

Conditions

Cancer Period Problem Acupuncture Stage I cancer Stage II cancer Stage III cancer Period Loss Due to Chemotherapy

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to find out whether it is practical (feasible) to use acupuncture to treat period loss (amenorrhea) caused by chemotherapy treatment in people with cancer. The researchers will look at how many participants enroll and complete the study. The researchers will also study how treatment with acupuncture affects the amount of time for the menstrual cycle to return and symptoms and quality of life related to amenorrhea.

Official Title

Acupuncture for Adolescent and Young Adult Cancer Patients: (AcuAYA)

Quick Facts

Study Start:2025-03-31

Study Completion:2027-03-31

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT06915116

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 39 Years

Sexes Eligible for Study:FEMALE

Accepts Healthy Volunteers:No

Standard Ages:ADULT

Inclusion Criteria	Exclusion Criteria
* English speaking women under the age of 40, with a history of stage I, II, or III cancer at the age of 18-39 * Premenopausal status with regular menstruation at the time of diagnosis by patient report * Completed chemotherapy within the past year * Report cessation of menses during or after chemotherapy and have not experienced menses recovery at the time of enrollment. * Have been without menses for at least 3 months following the completion of chemotherapy * Willing to adhere to all study-related procedures, including randomization to one of the two possible arms: acupuncture and WLC	* Metastatic cancer (stage IV) * Had been pregnant or lactating within 3 months prior to enrollment * History of hysterectomy or oophorectomy * Ongoing or planned radiation or surgery within 4 months from randomization * Use of acupuncture for menses recovery within 3 months of enrollment * Had been or will be receiving ovarian suppression medicine, such as leuprolide (Lupron) and goserelin (Zoladex), or hormonal contraception drugs within 3 months of enrollment or during the study period

Inclusion Criteria

Exclusion Criteria

* English speaking women under the age of 40, with a history of stage I, II, or III cancer at the age of 18-39
* Premenopausal status with regular menstruation at the time of diagnosis by patient report
* Completed chemotherapy within the past year
* Report cessation of menses during or after chemotherapy and have not experienced menses recovery at the time of enrollment.
* Have been without menses for at least 3 months following the completion of chemotherapy
* Willing to adhere to all study-related procedures, including randomization to one of the two possible arms: acupuncture and WLC

* Metastatic cancer (stage IV)
* Had been pregnant or lactating within 3 months prior to enrollment
* History of hysterectomy or oophorectomy
* Ongoing or planned radiation or surgery within 4 months from randomization
* Use of acupuncture for menses recovery within 3 months of enrollment
* Had been or will be receiving ovarian suppression medicine, such as leuprolide (Lupron) and goserelin (Zoladex), or hormonal contraception drugs within 3 months of enrollment or during the study period

Contacts and Locations

Study Contact

Jun Mao, MD, MSCE

CONTACT

646-608-8553

maoj@mskcc.org

William Tap, MD

CONTACT

646-888-4163

Principal Investigator

Jun Mao, MD, MSCE

PRINCIPAL_INVESTIGATOR

Memorial Sloan Kettering Cancer Center

Study Locations (Sites)

Memorial Sloan Kettering Basking Ridge (All Protocol Activities)

Basking Ridge, New Jersey, 07920

United States

Memorial Sloan Kettering Monmouth (All protocol activities)

Middletown, New Jersey, 07748

United States

Memorial Sloan Kettering Bergen (All Protocol Activities)

Montvale, New Jersey, 07645

United States

Memorial Sloan Kettering Suffolk- Commack (All Protocol Activities)

Commack, New York, 11725

United States

Memorial Sloan Kettering Westchester (All Protocol Activities)

Harrison, New York, 10604

United States

Memorial Sloan Kettering Cancer Center (All Protocol Activities)

New York, New York, 10065

United States

Memorial Sloan Kettering Nassau (All Protocol Activities)

Rockville Centre, New York, 11553

United States

Collaborators and Investigators

Sponsor: Memorial Sloan Kettering Cancer Center

Jun Mao, MD, MSCE, PRINCIPAL_INVESTIGATOR, Memorial Sloan Kettering Cancer Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-03-31

Study Completion Date2027-03-31

Study Record Updates

Study Start Date2025-03-31

Study Completion Date2027-03-31

Terms related to this study

Keywords Provided by Researchers

Acupuncture
Stage I cancer
Stage II cancer
Stage III cancer
Period Loss Due to Chemotherapy

Additional Relevant MeSH Terms

Cancer
Period Problem