RECRUITING

Micromanaging Human Sleep Physiology to Treat Sleep Apnea and Other Disorders

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study will examine whether a combination of breathing training during wake and targeted reactivation of the training during sleep can induce breathing changes during sleep and subsequent cognitive benefits during wake. Participants with obstructive sleep apnea (who have not yet been treated for sleep apnea) will be recruited. Participants will engage in breath training for one week in their own homes and to record their sleep at home using commercially available mobile devices and subsequently have their sleep monitored for one night of polysomnography recordings plus targeted reactivation in a laboratory setting.

Official Title

Micromanaging Human Sleep Physiology to Treat Sleep Apnea and Other Disorders

Quick Facts

Study Start:2025-04-03
Study Completion:2027-04
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06926036

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 60 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Right-handed, English-speaking adults, 18-60 years old who report normal hearing during sleep
  2. 2. Participants with suspected obstructive sleep apnea (OSA) (including those who have been diagnosed by a physician and those whose self-reported symptoms of OSA on the STOP-BANG questionnaire classify them as being "individuals with intermediate to high risk".
  3. 3. No report of any other sleep disorder besides OSA.
  4. 4. No report of any neurological or cardiometabolic diseases or disorders.
  5. 5. Not currently under active treatment for sleep apnea.
  6. 6. BMI ≤ 40.
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Ken A Paller, PhD
CONTACT
847-467-3370
kap@northwestern.edu

Principal Investigator

Ken A Paller, PhD
PRINCIPAL_INVESTIGATOR
Northwestern University

Study Locations (Sites)

Northwestern University
Chicago, Illinois, 60611
United States

Collaborators and Investigators

Sponsor: Northwestern University

  • Ken A Paller, PhD, PRINCIPAL_INVESTIGATOR, Northwestern University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-04-03
Study Completion Date2027-04

Study Record Updates

Study Start Date2025-04-03
Study Completion Date2027-04

Terms related to this study

Keywords Provided by Researchers

  • sleep
  • sleep apnea obstructive (OSA)

Additional Relevant MeSH Terms

  • Sleep Apnea Obstructive (OSA)