Occupational Cancer Screening in Firefighters: A Pilot Study Within the Inova Health System

Description

The purpose of this study is to further understand the clinical impact and follow-up steps that may be required based on using whole-body Magnetic Resonance Imaging (MRI) or whole-body ultrasound and blood tests to detect multiple cancers in firefighters. This study involves an investigational test (cancer blood test) that has not been approved by the U.S. Food and Drug Administration (FDA). Whole-body MRI and whole-body ultrasound are approved by the U.S. Food and Drug Administration (FDA) to be used in the diagnosis of some cancers and is approved for adults and children who present other signs of potential disease. In this study, however, the whole-body MRI and the whole-body ultrasound are considered investigational devices because they are not yet approved for use in healthy adults with no other cancer indications.

Conditions

Cancer

Study Overview

Study Details

Study overview

The purpose of this study is to further understand the clinical impact and follow-up steps that may be required based on using whole-body Magnetic Resonance Imaging (MRI) or whole-body ultrasound and blood tests to detect multiple cancers in firefighters. This study involves an investigational test (cancer blood test) that has not been approved by the U.S. Food and Drug Administration (FDA). Whole-body MRI and whole-body ultrasound are approved by the U.S. Food and Drug Administration (FDA) to be used in the diagnosis of some cancers and is approved for adults and children who present other signs of potential disease. In this study, however, the whole-body MRI and the whole-body ultrasound are considered investigational devices because they are not yet approved for use in healthy adults with no other cancer indications.

Occupational Cancer Screening in Firefighters: A Pilot Study Within the Inova Health System

Occupational Cancer Screening in Firefighters: A Pilot Study Within the Inova Health System

Condition
Cancer
Intervention / Treatment

-

Contacts and Locations

Fairfax

Inova Schar Cancer - Saville Cancer Screening and Prevention Center, Fairfax, Virginia, United States, 22031

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age ≥ 35 years old
  • * at least 10 cumulative years working as a firefighter
  • * Completion of National Fire Protection Association (NFPA) physical examination within the past 6 months for active-duty firefighters (retired firefighters do not need to meet this criteria)
  • * Ability to understand and willing to sign informed consent
  • * Ability to understand and willing to sign the Health Insurance Portability and Accountability Act (HIPAA) Authorization
  • * Additional eligibility criteria in protocol
  • * No prior history of any invasive cancer within the previous 5 years (non-melanoma skin cancer and in situ carcinoma would still be eligible) and no current diagnostic workup for suspicion of cancer.
  • * Received a whole-body MRI, whole-body ultrasound, or been tested with a MCD within the past 1-year
  • * For women of childbearing potential, pregnancy
  • * Additional exclusion criteria in protocol

Ages Eligible for Study

35 Years to 85 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Inova Health Care Services,

Stephanie Van Bebber, STUDY_DIRECTOR, Inova Health System - Inova Schar Cancer

Rebecca Kaltman, MD, PRINCIPAL_INVESTIGATOR, Inova Health System - Saville Cancer Screening and Prevention Center

Study Record Dates

2028-09-30