RECRUITING

Occupational Cancer Screening in Firefighters: A Pilot Study Within the Inova Health System

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to further understand the clinical impact and follow-up steps that may be required based on using whole-body Magnetic Resonance Imaging (MRI) or whole-body ultrasound and blood tests to detect multiple cancers in firefighters. This study involves an investigational test (cancer blood test) that has not been approved by the U.S. Food and Drug Administration (FDA). Whole-body MRI and whole-body ultrasound are approved by the U.S. Food and Drug Administration (FDA) to be used in the diagnosis of some cancers and is approved for adults and children who present other signs of potential disease. In this study, however, the whole-body MRI and the whole-body ultrasound are considered investigational devices because they are not yet approved for use in healthy adults with no other cancer indications.

Official Title

Occupational Cancer Screening in Firefighters: A Pilot Study Within the Inova Health System

Quick Facts

Study Start:2025-02-11
Study Completion:2028-09-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06931561

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:35 Years to 85 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age ≥ 35 years old
  2. * at least 10 cumulative years working as a firefighter
  3. * Completion of National Fire Protection Association (NFPA) physical examination within the past 6 months for active-duty firefighters (retired firefighters do not need to meet this criteria)
  4. * Ability to understand and willing to sign informed consent
  5. * Ability to understand and willing to sign the Health Insurance Portability and Accountability Act (HIPAA) Authorization
  6. * Additional eligibility criteria in protocol
  1. * No prior history of any invasive cancer within the previous 5 years (non-melanoma skin cancer and in situ carcinoma would still be eligible) and no current diagnostic workup for suspicion of cancer.
  2. * Received a whole-body MRI, whole-body ultrasound, or been tested with a MCD within the past 1-year
  3. * For women of childbearing potential, pregnancy
  4. * Additional exclusion criteria in protocol

Contacts and Locations

Study Contact

Salman Baig
CONTACT
(571) 472-3500
salman.baig@inova.org
Bryan Bassig, PhD
CONTACT
(571) 472-3500
bryan.bassig@inova.org

Principal Investigator

Stephanie Van Bebber
STUDY_DIRECTOR
Inova Health System - Inova Schar Cancer
Rebecca Kaltman, MD
PRINCIPAL_INVESTIGATOR
Inova Health System - Saville Cancer Screening and Prevention Center

Study Locations (Sites)

Inova Schar Cancer - Saville Cancer Screening and Prevention Center
Fairfax, Virginia, 22031
United States

Collaborators and Investigators

Sponsor: Inova Health Care Services

  • Stephanie Van Bebber, STUDY_DIRECTOR, Inova Health System - Inova Schar Cancer
  • Rebecca Kaltman, MD, PRINCIPAL_INVESTIGATOR, Inova Health System - Saville Cancer Screening and Prevention Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-02-11
Study Completion Date2028-09-30

Study Record Updates

Study Start Date2025-02-11
Study Completion Date2028-09-30

Terms related to this study

Additional Relevant MeSH Terms

  • Cancer