RECRUITING

Effect of Flavored, Carbonated Drinks on Salivary Flow, Salivary Composition, and Taste Perceptions

Conditions

Taste Perception Saliva Production taste saliva food pairing salivary protein mucin salivary flow rate

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

To determine the effect of flavored, carbonated drinks on salivary flow rate, saliva composition, and taste perceptions compared with control drinks (water, carbonated water, non-carbonated)

Official Title

Effect of Flavored, Carbonated Drinks on Salivary Flow, Salivary Composition, and Taste Perceptions

Quick Facts

Study Start:2025-03-24

Study Completion:2025-06-29

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT06933290

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 45 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:Yes

Standard Ages:ADULT

Inclusion Criteria	Exclusion Criteria
* Subject is male or female * If female, subject is not pregnant or nursing (based on self-report) * Subject is 18-45 years of age, inclusive * Subject is a regular consumer of carbonated drinks (questionnaire) * Subject is willing to avoid alcohol consumption 24 hours prior to visits * Subject is willing to fast (no food or gum) for 2 hours prior to study sessions * Able to speak, write, and read English * Provision of written consent to participate	* Subject smokes, vapes, or uses any nicotine/tobacco products (or has quit for less than 6 months) * Subject currently has or recently had an illness (cold, flu, COVID) within the past month * Subject has a condition affecting the oral cavity such as Xerostomia (dry mouth), Sores/lesions, Untreated dental caries, Major dental implants/appliances (including dentures) * Subject has a reduced sense of taste (dysgeusia) or smell (parosmia) * Subject has a health condition that would interfere with the study as indicated on the general health questionnaire (GHQ) (including cardiovascular, renal, or metabolic diseases) * Subject has participated in a clinical trial within the past 30 days * Subject has participated in any PepsiCo trial within past 6 months * Subject has a condition or is taking medication that the investigator believes would interfere with his/her ability to provide informed consent, comply with the study protocol, which might confound the interpretation of the study results, or put the person at undue risk * Subject is employed by, or has a parent, guardian, or other immediate family member employed by a company that manufactures any products that compete with any PepsiCo product. If subject is unsure if a company would be considered a competitor to PepsiCo, they will be asked to please let the study investigator know the name of the other company and the nature of their relationship to that company before they sign the informed consent.

Inclusion Criteria

Exclusion Criteria

* Subject is male or female
* If female, subject is not pregnant or nursing (based on self-report)
* Subject is 18-45 years of age, inclusive
* Subject is a regular consumer of carbonated drinks (questionnaire)
* Subject is willing to avoid alcohol consumption 24 hours prior to visits
* Subject is willing to fast (no food or gum) for 2 hours prior to study sessions
* Able to speak, write, and read English
* Provision of written consent to participate

* Subject smokes, vapes, or uses any nicotine/tobacco products (or has quit for less than 6 months)
* Subject currently has or recently had an illness (cold, flu, COVID) within the past month
* Subject has a condition affecting the oral cavity such as Xerostomia (dry mouth), Sores/lesions, Untreated dental caries, Major dental implants/appliances (including dentures)
* Subject has a reduced sense of taste (dysgeusia) or smell (parosmia)
* Subject has a health condition that would interfere with the study as indicated on the general health questionnaire (GHQ) (including cardiovascular, renal, or metabolic diseases)
* Subject has participated in a clinical trial within the past 30 days
* Subject has participated in any PepsiCo trial within past 6 months
* Subject has a condition or is taking medication that the investigator believes would interfere with his/her ability to provide informed consent, comply with the study protocol, which might confound the interpretation of the study results, or put the person at undue risk
* Subject is employed by, or has a parent, guardian, or other immediate family member employed by a company that manufactures any products that compete with any PepsiCo product. If subject is unsure if a company would be considered a competitor to PepsiCo, they will be asked to please let the study investigator know the name of the other company and the nature of their relationship to that company before they sign the informed consent.

Contacts and Locations

Study Contact

Lindsay Baker, PhD

CONTACT

814-883-9454

Lindsay.Baker@pepsico.com

Principal Investigator

Lindsay Baker, PhD

PRINCIPAL_INVESTIGATOR

PepsiCo, Inc. Sports Science

Study Locations (Sites)

Gatorade Sports Science Institute

Valhalla, New York, 10595

United States

Collaborators and Investigators

Sponsor: PepsiCo Global R&D

Lindsay Baker, PhD, PRINCIPAL_INVESTIGATOR, PepsiCo, Inc. Sports Science

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-03-24

Study Completion Date2025-06-29

Study Record Updates

Study Start Date2025-03-24

Study Completion Date2025-06-29

Terms related to this study

Keywords Provided by Researchers

taste
saliva
food pairing
salivary protein
mucin
salivary flow rate

Additional Relevant MeSH Terms

Taste Perception
Saliva Production