Microplastic Exposure From Clear Aligner Wear (MPE)

Description

An observational longitudinal study measuring microplastic exposure and physiologic uptake in orthodontic patients receiving clear aligner treatment.

Conditions

Microplastic Exposure

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Study Overview

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Study Details

Study overview

An observational longitudinal study measuring microplastic exposure and physiologic uptake in orthodontic patients receiving clear aligner treatment.

Microplastic Exposure From Clear Aligner Wear: An In Vivo, Longitudinal Study of Orthodontic Patients

Microplastic Exposure From Clear Aligner Wear (MPE)

Condition
Microplastic Exposure
Intervention / Treatment

-

Contacts and Locations

Chapel Hill

University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States, 27599

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Individuals (all sexes, genders, races, and ethnicities) aged at least 10 years (in adult dentition) and at most 90 years
  • * Receiving comprehensive, Phase II orthodontic treatment with clear aligner therapy
  • * Stable physical health (ASA I or II), as determined by study coordinator or PI
  • * Able to comprehend and follow requirements of study (including availability on scheduled visit dates)
  • * Patient and parental consent (and assent for minors) for participation in the study
  • * Receiving orthodontic treatment with fixed appliances
  • * Receiving hybrid treatment with fixed appliances and aligners
  • * Receiving Phase I orthodontic treatment with fixed appliances
  • * Established history of severe xerostomia (dry mouth), severe periodontal disease with actively bleeding gums, significant oral abrasions/ulcers or growths, current alcohol abuse, and/or recreational drug abuse
  • * Other severe acute or chronic medical or psychiatric condition or laboratory abnormality that may increase risk associated with participation
  • * Drinking, eating, or brushing teeth within 1 hour of study visit
  • * Removing aligners within 1 hour of study visit
  • * Developmental or cognitive disability such that the patient cannot self-consent, comprehend, and follow the requirements of the study based on research site personnel's assessment

Ages Eligible for Study

10 Years to 90 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of North Carolina, Chapel Hill,

Laura A Jacox, DMD, PhD, MS, PRINCIPAL_INVESTIGATOR, University of North Carolina, Chapel Hill

Study Record Dates

2035-05