RECRUITING

Traumatic Hemothorax Drainage and Daily Lavage: Pilot Study

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Conditions

Hemothorax; Traumatic

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This HTX treatment study evaluates the effects of chest tube size and the benefits of daily irrigations on acute HTX. 20 acutely injured but stable trauma patients requiring a chest tube for HTX will be enrolled. Patients will be assigned a 28Fr or 14 Fr chest tube with serial lavage and drainage. The endpoints will be HTX volume (by CT scan), complications, additional interventions, hospital length of stay, chest tube duration, provider feedback, and patient-reported outcomes.

Official Title

Traumatic Hemothorax Treatment With 14-Fr Pigtail Catheters or Large Bore (~28Fr) Chest Tubes With Daily Irrigation: A Pilot Single-Arm Intervention Study

Quick Facts

Study Start:2025-03-03
Study Completion:2027-08-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06937450

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:15 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Able to provide consent for the research study
  2. 2. More than 15 years of age
  3. 3. Presence of acute traumatic HTX or HTX-PTX diagnosed on chest CT scan within 24 hours of injury and clinical indication for drainage (hemothorax of moderate or large size greater then 300 mL)
  4. 4. Hemodynamic stability (heart rate 120 beats per minute; systolic blood pressure 90 mmHg)
  5. 5. Bilateral or unilateral hemothorax of greater than 300 mL HTX by Mergo Formula from chest CT
  6. 6. Able to complete the entire study including randomization, tube placement, lavages and final CT Scan.
  1. 1. Less than 15 years of Age
  2. 2. Prisoner
  3. 3. Pregnant due to the risk of CT scans
  4. 4. HTX or HTX-PTX not requiring drainage or drainage performed prior to randomization/enrollment
  5. 5. Patients undergoing operative intervention (i.e. thoracotomy) as initial management of hemothorax (6) Persistent hemodynamic instability after initial resuscitation and CT imaging

Contacts and Locations

Study Contact

Jeremy W Cannon, MD
CONTACT
215-66-27320
jeremy.cannon@pennmedicine.upenn.edu
Phillp Kemp Bohan, MD
CONTACT
267-909-3573
Phillip.Kempbohn@Pennmedicine.upenn.edu

Principal Investigator

Jeremy Cannon, MD
PRINCIPAL_INVESTIGATOR
University of Pennsylvania

Study Locations (Sites)

Penn Presbyterian Medical Center
Philadelphia, Pennsylvania, 19104
United States

Collaborators and Investigators

Sponsor: University of Pennsylvania

  • Jeremy Cannon, MD, PRINCIPAL_INVESTIGATOR, University of Pennsylvania

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-03-03
Study Completion Date2027-08-01

Study Record Updates

Study Start Date2025-03-03
Study Completion Date2027-08-01

Terms related to this study

Additional Relevant MeSH Terms

  • Hemothorax; Traumatic