Pilot Haskap Metabolite Timing Project

Description

Diet is a key factor in managing health and individuals at risk of developing metabolic syndrome or other chronic diseases have the opportunity to use diet as a tool to improve their health. This can be complicated when considering the numerous variables that impact digestion and absorption of key health-promoting compounds in foods. One of these variables is the gut microbiome, a microbial community in the digestive tract that interacts with the foods we consume. The mechanisms the microbiome uses to interact with bioactive compounds in foods, like polyphenols, can modulate the health-promoting benefits of polyphenols. Polyphenols are secondary plant metabolites, commonly found in fruit, legumes, chocolate, coffee, and nuts among other foods that have been shown to improve cardiovascular and metabolic health, as well as reduce inflammation and oxidative stress.

Conditions

Microbial Colonization, Metabolic Disease, Digestion

Study Overview

Study Details

Study overview

Diet is a key factor in managing health and individuals at risk of developing metabolic syndrome or other chronic diseases have the opportunity to use diet as a tool to improve their health. This can be complicated when considering the numerous variables that impact digestion and absorption of key health-promoting compounds in foods. One of these variables is the gut microbiome, a microbial community in the digestive tract that interacts with the foods we consume. The mechanisms the microbiome uses to interact with bioactive compounds in foods, like polyphenols, can modulate the health-promoting benefits of polyphenols. Polyphenols are secondary plant metabolites, commonly found in fruit, legumes, chocolate, coffee, and nuts among other foods that have been shown to improve cardiovascular and metabolic health, as well as reduce inflammation and oxidative stress.

Haskap Berry Derived Plasma Metabolites - Pilot Timing Project

Pilot Haskap Metabolite Timing Project

Condition
Microbial Colonization
Intervention / Treatment

-

Contacts and Locations

Bozeman

Montana State University, Bozeman, Montana, United States, 59717

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * 18-45 years old
  • * Body mass index (BMI) between 18-30 kg/m\^2
  • * allergy to Haskap berries
  • * have taken antibiotics in the last 90 days
  • * take dietary supplements
  • * have adverse events from blood draws
  • * take medication to lower cholesterol, inflammation, lipids
  • * smoke cigarettes
  • * pregnant and/or lactating
  • * have diabetes
  • * are unwilling to follow a no-polyphenolic diet for 10 days

Ages Eligible for Study

18 Years to 45 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Montana State University,

Mary P Miles, PhD, PRINCIPAL_INVESTIGATOR, Montana State University

Study Record Dates

2025-09-01