RECRUITING

Neurophysiological Benefits of Live Music for Early Alzheimer's Patients and Their Caregivers

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study aims to investigate the neurophysiological effects of live music on individuals with early Alzheimer's Disease (AD), dementia, and/or mild cognitive impairment (MCI) and their caregivers. Heart rate (HR), heart rate variability (HRV), and brain activity will be measured as participant-caregiver dyads listen to preferred and improvised music performed by professional musicians. Investigators will leverage various measurement techniques including, but not limited to, electroencephalography (EEG), behavioral, surveys, and physiological monitoring to study the impact of live music on anxiety in AD and inter-dyad synchrony.

Official Title

Neurophysiological Benefits of Live Music for Early Alzheimer's Patients and Their Caregivers

Quick Facts

Study Start:2025-01-28
Study Completion:2025-08
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06940687

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:50 Years to 80 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Clinical Dementia Rating 0.5 - 2
  2. * Be a person with or caregiver to a person with a diagnosis of early Alzheimer's Disease, mild dementia, and/or mild cognitive impairment (MCI)
  3. * Able to provide informed consent
  4. * Willing to wear an EEG headset and heart rate monitoring devices
  5. * Willing to possibly have small patches of body / facial hair shaved to accommodate administration of heart rate monitoring devices
  6. * Willing to answer survey questions about topics related to the study
  7. * Willing to be audio / video recorded
  1. * Clinical Dementia Rating \<0.5 or \> 2
  2. * Unable to provide informed consent
  3. * Endorsing suicidal ideation (SI), self-injurious behavior, or homicidal ideation (HI) above the threshold defined in the "Risk Reduction and Safety Plan"
  4. * Participating in another clinical trial studying AD and/or Dementia
  5. * Starting a new prescription medication in the last 6 months
  6. * Prescribed Benzodiazepines on an as needed basis

Contacts and Locations

Study Contact

AZA Allsop, MD, PhD
CONTACT
240-422-3289
Aza.allsop@yale.edu
AZA Lab
CONTACT
203-903-2157
azalab@yale.edu

Principal Investigator

AZA Allsop, MD, PhD
PRINCIPAL_INVESTIGATOR
Yale University

Study Locations (Sites)

Firehouse 12 Studios
New Haven, Connecticut, 06510
United States
Musical Intervention Studios
New Haven, Connecticut, 06520
United States

Collaborators and Investigators

Sponsor: Yale University

  • AZA Allsop, MD, PhD, PRINCIPAL_INVESTIGATOR, Yale University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-01-28
Study Completion Date2025-08

Study Record Updates

Study Start Date2025-01-28
Study Completion Date2025-08

Terms related to this study

Keywords Provided by Researchers

  • Live Music
  • EEG
  • EKG/ECG
  • Anxiety
  • Connectedness
  • Social Connection

Additional Relevant MeSH Terms

  • Alzheimer Disease
  • Dementia
  • Mild Cognitive Impairment
  • Peer-bonded Caregiver
  • Caregiver