RECRUITING

How Simplified Language Affects Comprehension and Learning in Young Children With Down Syndrome

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The long-term study goal is to experimentally evaluate the components (and likely active ingredients) of early language interventions for young children with Down syndrome (DS). The overall objective is to determine how single-word and telegraphic simplification affects real-time language processing and word learning in young children with DS (relative to full, grammatical utterances). The proposed project will investigate three specific aims: 1) Determine how single-word and telegraphic simplification affects language processing. 2) Determine how single-word and telegraphic simplification affects word learning. 3) Evaluate child characteristics that may moderate the effects of linguistic simplification on language processing and word learning. Aim 1 will test the hypothesis that children with DS will process grammatical utterances faster and more accurately than telegraphic or single-word utterances. Aim 2 will test the hypothesis that overall, children will demonstrate better word learning in the grammatical compared to the single-word and telegraphic conditions. Aim 3 will test the hypothesis that receptive language and nonverbal cognitive abilities will be significant moderators, such that children with stronger linguistic and cognitive skills will show the greatest benefit from grammatical input but children with lower linguistic and cognitive scores will perform similarly across conditions.

Official Title

How Single-Word and Telegraphic Simplification Affects Language Processing and Word Learning in Young Children With Down Syndrome

Quick Facts

Study Start:2025-01-01
Study Completion:2027-05-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06951516

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:2 Years to 7 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. * Down syndrome
  1. * Acquired brain injury

Contacts and Locations

Study Contact

Courtney Venker, PhD
CONTACT
517-884-2259
cvenker@msu.edu
Jennifer Johnson, M.S.
CONTACT
517-884-2259
jrj@msu.edu

Principal Investigator

Courtney Venker, PhD
PRINCIPAL_INVESTIGATOR
Michigan State University

Study Locations (Sites)

Michigan State University
East Lansing, Michigan, 48824
United States

Collaborators and Investigators

Sponsor: Michigan State University

  • Courtney Venker, PhD, PRINCIPAL_INVESTIGATOR, Michigan State University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-01-01
Study Completion Date2027-05-31

Study Record Updates

Study Start Date2025-01-01
Study Completion Date2027-05-31

Terms related to this study

Keywords Provided by Researchers

  • Down syndrome
  • language development
  • language processing
  • language input

Additional Relevant MeSH Terms

  • Down Syndrome