RECRUITING

Optimizing Aerobic Fitness in Older Adults

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Hospitalization and treatment for cardiovascular disease is one of the main contributors to disability in older adults. Moderate intensity continuous aerobic and resistance training have been the cornerstone of cardiac rehabilitation (CR) for decades to remediate hospital-acquired functional deficits, but some groups receive less or minimal functional benefit from this training. The proposed studies seek to optimize recovery of aerobic fitness and physical function among older cardiac patients using a novel high intensity training regimen with the long-term goal of reducing subsequent disability and improving clinical outcomes.

Official Title

Optimizing Aerobic Fitness and Functional Response to Exercise in Older Adults

Quick Facts

Study Start:2025-04-17
Study Completion:2030-03-15
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06951620

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * \>65 years old
  2. * ambulatory
  3. * enrolled in CR at our center following a recent clinical diagnosis of myocardial infarction or percutaneous intervention will be recruited
  1. * have an active malignancy (excluding non-melanoma skin cancer or low grade prostate cancer under surveillance)
  2. * unwilling to comply with the exercise prescription they may be assigned to
  3. * have a submaximal performance on entry exercise tolerance test, defined as respiratory exchange ratio \<1.0

Contacts and Locations

Study Contact

Patrick Savage, Research Coordinator
CONTACT
802-847-4545
patrick.savage@uvmhealth.org

Principal Investigator

Sherrie Khadanga MD, Principal Investigator, MD
PRINCIPAL_INVESTIGATOR
University of Vermont Medical Center

Study Locations (Sites)

UVMMC Cardiac Rehabilitation
South Burlington, Vermont, 05403
United States

Collaborators and Investigators

Sponsor: University of Vermont Medical Center

  • Sherrie Khadanga MD, Principal Investigator, MD, PRINCIPAL_INVESTIGATOR, University of Vermont Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-04-17
Study Completion Date2030-03-15

Study Record Updates

Study Start Date2025-04-17
Study Completion Date2030-03-15

Terms related to this study

Keywords Provided by Researchers

  • cardiac rehabilitation
  • HIIT
  • MICT
  • exercise in older adults
  • aerobic capacity

Additional Relevant MeSH Terms

  • Aerobic Capacity
  • High Intensity Interval Training