RECRUITING

Investigating Periprosthetic Fracture Cultures in Arthroplasty

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study aims to improve how doctors diagnose infections in patients with broken bones around joint replacements. Currently, there are no clear guidelines to help determine when an infection is present, making treatment decisions difficult. By studying how often infections are found through lab tests and identifying factors that predict infection, the investigators hope to create better ways to diagnose and care for these patients.

Official Title

Investigating Periprosthetic Fracture Culture Positivity in Patients With Hip and Knee Arthroplasties

Quick Facts

Study Start:2025-10-01
Study Completion:2027-10-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06952738

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Adult patients (\>18 years old) with periprosthetic fractures around primary or revision hip or knee arthroplasty
  2. * Patients requiring operative management for these fractures (fixation or revision arthroplasty)
  3. * Patients presenting to the University of Chicago Medical Center during two (2) year period (October 2025 to October 2027)
  1. * Patients undergoing non-operative management for periprosthetic fractures
  2. * Any documented or reported history of past prosthetic joint infection of the involved joint
  3. * Sinus tract at the time of presentation at the involved joint

Contacts and Locations

Study Contact

Malik J Scott, BA
CONTACT
773-834-0822
mjscott1@uchicago.edu
Vincent Buckman, BS
CONTACT
vincent.buckman@uchicagomedicine.org

Principal Investigator

Sara Wallace, MD
PRINCIPAL_INVESTIGATOR
The University of Chicago Department of Orthopaedic Surgery

Study Locations (Sites)

The University of Chicago Medical Center
Chicago, Illinois, 60637
United States

Collaborators and Investigators

Sponsor: University of Chicago

  • Sara Wallace, MD, PRINCIPAL_INVESTIGATOR, The University of Chicago Department of Orthopaedic Surgery

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-10-01
Study Completion Date2027-10-31

Study Record Updates

Study Start Date2025-10-01
Study Completion Date2027-10-31

Terms related to this study

Keywords Provided by Researchers

  • Periprosthetic fractures
  • synovial fluid
  • prosthetic joint infections

Additional Relevant MeSH Terms

  • Periprosthetic Fracture Around Prosthetic Joint Implant