Investigating Periprosthetic Fracture Cultures in Arthroplasty

Description

This study aims to improve how doctors diagnose infections in patients with broken bones around joint replacements. Currently, there are no clear guidelines to help determine when an infection is present, making treatment decisions difficult. By studying how often infections are found through lab tests and identifying factors that predict infection, the investigators hope to create better ways to diagnose and care for these patients.

Conditions

Periprosthetic Fracture Around Prosthetic Joint Implant

Study Overview

Study Details

Study overview

This study aims to improve how doctors diagnose infections in patients with broken bones around joint replacements. Currently, there are no clear guidelines to help determine when an infection is present, making treatment decisions difficult. By studying how often infections are found through lab tests and identifying factors that predict infection, the investigators hope to create better ways to diagnose and care for these patients.

Investigating Periprosthetic Fracture Culture Positivity in Patients With Hip and Knee Arthroplasties

Investigating Periprosthetic Fracture Cultures in Arthroplasty

Condition
Periprosthetic Fracture Around Prosthetic Joint Implant
Intervention / Treatment

-

Contacts and Locations

Chicago

The University of Chicago Medical Center, Chicago, Illinois, United States, 60637

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Adult patients (\>18 years old) with periprosthetic fractures around primary or revision hip or knee arthroplasty
  • * Patients requiring operative management for these fractures (fixation or revision arthroplasty)
  • * Patients presenting to the University of Chicago Medical Center during two (2) year period (October 2025 to October 2027)
  • * Patients undergoing non-operative management for periprosthetic fractures
  • * Any documented or reported history of past prosthetic joint infection of the involved joint
  • * Sinus tract at the time of presentation at the involved joint

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Chicago,

Sara Wallace, MD, PRINCIPAL_INVESTIGATOR, The University of Chicago Department of Orthopaedic Surgery

Study Record Dates

2027-10-31