RECRUITING

Investigating Brain Function in People With and Without Visual Snow Syndrome Using Adaptation to Visual Stimuli

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Conditions

Visual Snow SyndromeMigraineHealthyVisual SnowFloatersPalinopsiaPhotophobiaNyctalopiaEntoptic phenomenaVisual trailingAdaptationMagnetic resonance spectroscopyMRSMagnetic resonance imagingMRIUniversity of MinnesotaAfterimagesPoor night visionLight sensitivityPersistent positive visual phenomenaStatic

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this study is to learn more about the brain pathways and activity involved in creating Visual Snow Syndrome (VSS). The main questions it aims to answer are: * Does VSS arise from spontaneous activity in brain pathways? * Where in the brain does the activity contributing to VSS arise? * How does brain activity contribute to VSS? Participants will: 1. Undergo assessments and questionnaires to understand visual and mental symptoms, cognitive, and sensory function. 2. Make visual judgements based on images presented to them both inside and outside a magnetic resonance imaging (MRI) machine. 3. Undergo scanning of their brain while inside of an MRI machine.

Official Title

Visual Perception in Visual Snow Syndrome

Quick Facts

Study Start:2025-05-31
Study Completion:2030-03-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06961864

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 60 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Michael-Paul Schallmo, Ph.D.
CONTACT
(612) 273-9130
schallmolab@umn.edu
Hannah Moser, Ph.D.
CONTACT
schallmolab@umn.edu

Principal Investigator

Michael-Paul Schallmo, Ph.D.
PRINCIPAL_INVESTIGATOR
University of Minnesota, Department of Psychiatry and Behavioral Sciences
Stephen A Engel, Ph.D.
STUDY_CHAIR
University of Minnesota, Department of Psychology
Michael S Lee, M.D.
STUDY_CHAIR
University of Minnesota, Department of Ophthalmology and Visual Neurosciences
Abby Metzler, M.D.
STUDY_CHAIR
University of Minnesota, Department of Neurology
Malgorzata Marjanska, Ph.D.
STUDY_CHAIR
University of Minnesota, Department of Radiology
Carrie E Robertson, M.D.
STUDY_CHAIR
Mayo Clinic, Rochester, Department of Neurology

Study Locations (Sites)

University of Minnesota
Minneapolis, Minnesota, 55455
United States

Collaborators and Investigators

Sponsor: University of Minnesota

  • Michael-Paul Schallmo, Ph.D., PRINCIPAL_INVESTIGATOR, University of Minnesota, Department of Psychiatry and Behavioral Sciences
  • Stephen A Engel, Ph.D., STUDY_CHAIR, University of Minnesota, Department of Psychology
  • Michael S Lee, M.D., STUDY_CHAIR, University of Minnesota, Department of Ophthalmology and Visual Neurosciences
  • Abby Metzler, M.D., STUDY_CHAIR, University of Minnesota, Department of Neurology
  • Malgorzata Marjanska, Ph.D., STUDY_CHAIR, University of Minnesota, Department of Radiology
  • Carrie E Robertson, M.D., STUDY_CHAIR, Mayo Clinic, Rochester, Department of Neurology

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-05-31
Study Completion Date2030-03-31

Study Record Updates

Study Start Date2025-05-31
Study Completion Date2030-03-31

Terms related to this study

Keywords Provided by Researchers

  • Visual Snow Syndrome
  • Visual Snow
  • Migraine
  • Floaters
  • Palinopsia
  • Photophobia
  • Nyctalopia
  • Entoptic phenomena
  • Visual trailing
  • Adaptation
  • Magnetic resonance spectroscopy
  • MRS
  • Magnetic resonance imaging
  • MRI
  • University of Minnesota
  • Afterimages
  • Poor night vision
  • Light sensitivity
  • Persistent positive visual phenomena
  • Static

Additional Relevant MeSH Terms

  • Visual Snow Syndrome
  • Migraine
  • Healthy