Wearable Sensors to Detect Atypical Muscle Activation in Young Infants

Description

The purpose of this study is to see if wearable sensor technology can be used to evaluate muscle activity and/or identify atypical muscle tone in infants up to 48 weeks postmenstrual age (8 weeks corrected age). These sensors are placed on the surface of the skin and record data about a child's body movements and muscle activity.

Conditions

Neuromuscular Disorders, Motor Development, Muscle Tone

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Study Overview

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Study Details

Study overview

The purpose of this study is to see if wearable sensor technology can be used to evaluate muscle activity and/or identify atypical muscle tone in infants up to 48 weeks postmenstrual age (8 weeks corrected age). These sensors are placed on the surface of the skin and record data about a child's body movements and muscle activity.

Early Detection of Atypical Neuromuscular Development Using Wearable Sensors and Video: A Comparative Analysis of Muscle and Motion

Wearable Sensors to Detect Atypical Muscle Activation in Young Infants

Condition
Neuromuscular Disorders
Intervention / Treatment

-

Contacts and Locations

Chicago

Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, United States, 60611

Chicago

Shirley Ryan AbilityLab, Chicago, Illinois, United States, 60611

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * For Infants with low tone:
  • * Hospitalized in the NICU
  • * AND \>38 weeks post-menstrual age
  • * AND abnormal normal brain imaging OR Apgar score \<7 at five minutes with umbilical cord pH (if obtained) \<7.15
  • * AND 2 or more warning signs for muscle tone or posture using the HNNE short form
  • * AND legal guardian able and willing to give written consent and comply with study procedures
  • * For Infants with typical tone:
  • * Born at 38-41 weeks of gestation
  • * AND hospitalized after birth in the NICU OR well newborn nursery
  • * AND infants with appropriate for gestational age birth weight
  • * AND HNNE exam (short proforma) normal with no warning signs for any parameter
  • * AND legal guardian able and willing to give written consent and comply with study procedures.
  • * Infants of Both Low Tone and Typical Tone Cohorts:
  • * Missing or incomplete limbs (such as from amputation or congenital limb defects).
  • * Open wounds or skin breakdown on the limbs or torso.
  • * Presence of known genetic syndrome or congenital anomalies requiring surgery or affecting function
  • * Use of sedative medications (may include phenobarbital if level stable and therapeutic)
  • * Legal guardian unable to give written consent and comply with study procedures.
  • * Does not receive medical clearance from a physician to participate in the study if the individual is receiving inpatient care.

Ages Eligible for Study

0 Months to 8 Weeks

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Shirley Ryan AbilityLab,

Arun Jayaraman, PT, PhD, PRINCIPAL_INVESTIGATOR, Shirley Ryan AbilityLab

Study Record Dates

2026-05-31