Non-Narcotic Pain Control After ACL Reconstruction

Description

This is a double-blind randomized controlled trial of standard of care therapy, either oral ketorolac (experimental group) or oral oxycodone (control group) to demonstrate efficacy in reducing the percentage of narcotic doses taken and documenting the number of patients with no exposure to any narcotics (take zero oxycodone) after undergoing primary knee ACL reconstruction outpatient surgery.

Conditions

ACL - Anterior Cruciate Ligament Rupture, ACL Injuries

Study Overview

Study Details

Study overview

This is a double-blind randomized controlled trial of standard of care therapy, either oral ketorolac (experimental group) or oral oxycodone (control group) to demonstrate efficacy in reducing the percentage of narcotic doses taken and documenting the number of patients with no exposure to any narcotics (take zero oxycodone) after undergoing primary knee ACL reconstruction outpatient surgery.

Non-Narcotic Pain Control After ACL Reconstruction

Non-Narcotic Pain Control After ACL Reconstruction

Condition
ACL - Anterior Cruciate Ligament Rupture
Intervention / Treatment

-

Contacts and Locations

Coral Springs

Cleveland Clinic Coral Springs, Coral Springs, Florida, United States, 33067

Garfield

Cleveland clinic sports medicine, Garfield, Ohio, United States, 44125

Strongsville

Cleveland Clinic, Strongsville, Ohio, United States, 44136

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Provision of signed and dated informed consent form
  • * Stated willingness to comply with all study procedures and availability for the duration of the study
  • * Male or female, aged 15-55 years
  • * Primary Autograft ACL surgery
  • * Ability to take oral medication and willingness to patriciate in a virtual 1 and 2 week follow-up pill counts
  • * Provision of signed and dated informed consent form
  • * Stated willingness to comply with all study procedures and availability for t the duration of the study
  • * Male or female, aged 15-55 years
  • * Primary Autograft ACL surgery
  • * Ability to take oral medication and willingness to patriciate in a virtual 1 and 2 week follow-up pill counts

Ages Eligible for Study

15 Years to 55 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

The Cleveland Clinic,

Kurt P Spindler, MD, PRINCIPAL_INVESTIGATOR, The Cleveland Clinic

Study Record Dates

2025-12-31