RECRUITING

Post-Stroke Aphasia TMS

Conditions

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The investigator proposes to examine the effects of excitatory transcranial magnetic stimulation (TMS) combined with semantic feature analysis (SFA) language therapy to improve word-finding abilities in stroke survivors with aphasia (SWA).

Official Title

Precision Neuromodulation in Post-Stroke Aphasia Using TMS

Quick Facts

Study Start:2025-09-01

Study Completion:2036-12-31

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT06974279

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:No

Standard Ages:ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
* Diagnosed with left hemisphere stroke * Consent date \>= 1 month after stroke onset * Fluent in English * 18 years of age or older	* Severe cognitive, auditory or visual impairments that would preclude cognitive and language testing * Presence of major untreated or unstable psychiatric disease (e.g. schizophrenia, bipolar disease) * A chronic medical condition that is not treated or is unstable * The presence of cardiac stimulators or pacemakers or intracardiac lines, neurostimulators, medication infusion device, any other implants near the scalp (e.g., cochlear implants) or in the eye, metal in the body (e.g., splinters, fragments, clips) * Pregnancy * History of skull fractures, or skin diseases * History of ongoing or unmanaged seizures * Presence of factors that potentially decrease seizure thresholds: on pro-convulsant medications, untreated sleep deprivation or insomnia, ongoing alcoholism or illegal drug abuse (e.g., cocaine or MDMA users) * History of dyslexia or other developmental learning disabilities

Inclusion Criteria

Exclusion Criteria

* Diagnosed with left hemisphere stroke
* Consent date \>= 1 month after stroke onset
* Fluent in English
* 18 years of age or older

* Severe cognitive, auditory or visual impairments that would preclude cognitive and language testing
* Presence of major untreated or unstable psychiatric disease (e.g. schizophrenia, bipolar disease)
* A chronic medical condition that is not treated or is unstable
* The presence of cardiac stimulators or pacemakers or intracardiac lines, neurostimulators, medication infusion device, any other implants near the scalp (e.g., cochlear implants) or in the eye, metal in the body (e.g., splinters, fragments, clips)
* Pregnancy
* History of skull fractures, or skin diseases
* History of ongoing or unmanaged seizures
* Presence of factors that potentially decrease seizure thresholds: on pro-convulsant medications, untreated sleep deprivation or insomnia, ongoing alcoholism or illegal drug abuse (e.g., cocaine or MDMA users)
* History of dyslexia or other developmental learning disabilities

Contacts and Locations

Study Contact

Sidney Schoenrock, MA

CONTACT

414-955-7579

sschoenrock@mcw.edu

Ari Hjelmeseth

CONTACT

414-955-7578

ahjelmeseth@mcw.edu

Study Locations (Sites)

Medical College of Wisconsin

Milwaukee, Wisconsin, 53226

United States

Collaborators and Investigators

Sponsor: Medical College of Wisconsin

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-09-01

Study Completion Date2036-12-31

Study Record Updates

Study Start Date2025-09-01

Study Completion Date2036-12-31

Terms related to this study

Keywords Provided by Researchers

Aphasia
Stroke
Language
TMS

Additional Relevant MeSH Terms

Aphasia
Stroke
Language