RECRUITING

A Long Term Follow-up Study of TScan TCR-T Products

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this Long-Term Follow-Up (LTFU) study is to monitor participants who have previously received TSC-100 or TSC-101 TCR-T therapies in the TSCAN-001 study. Participants will be monitored for 15 years from the date of TCR-T cell therapy administration to assess long-term safety and efficacy.

Official Title

A Long-term Follow-up Study to Assess Safety in Participants Who Received an Investigational T-Cell Receptor Engineered T-Cell (TCR-T) Product

Quick Facts

Study Start:2025-09-09
Study Completion:2040-09
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06976736

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 110 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Participants who received a TCR-T cellular therapy in a clinical study sponsored by TScan Therapeutics.
  2. * Signed informed consent.
  1. * None

Contacts and Locations

Study Contact

Madhavi Desai
CONTACT
(857) 399-9832
medicalaffairs@tscan.com

Principal Investigator

Michelle Matzko, MD
STUDY_DIRECTOR
Medical Monitor

Study Locations (Sites)

City of Hope
Duarte, California, 91010
United States
Mount Sinai
New York, New York, 10029-6696
United States

Collaborators and Investigators

Sponsor: TScan Therapeutics, Inc.

  • Michelle Matzko, MD, STUDY_DIRECTOR, Medical Monitor

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-09-09
Study Completion Date2040-09

Study Record Updates

Study Start Date2025-09-09
Study Completion Date2040-09

Terms related to this study

Keywords Provided by Researchers

  • TSCAN
  • Cell Therapies
  • TCR-T Cell Therapy
  • Long Term Follow-Up (LTFU)
  • TSC-101
  • TSC-100
  • TSCAN-001

Additional Relevant MeSH Terms

  • AML
  • ALL
  • MDS