Matching Treatments to Cognitive Deficits in Offenders With Substance Use Disorders

Description

The goal of this clinical trial is to investigate the effect of two types of cognitive remediation training on real-world behavioral outcomes including substance use, institutional adjustment, and recidivism following release from prison. Each training type is designed to target one of two subtypes of antisocial criminal offenders, who are characterized by either: 1) Attention to context-based deficits, or 2) Affective cognitive control-based deficits. The main questions it aims to answer are: Does matching deficit type with targeted cognitive training improve outcomes (relative to mismatched training)? What are the functional brain mechanisms that underlie treatment change? Participants will: Be assigned to cognitive training that either does or does not match their deficit type. Complete six one-hour sessions of cognitive skills training. Complete pre and post-training behavioral tasks assessing self-regulation deficits. Complete structural MRI scans and functional MRI scans assessing cognitive control. Complete post-treatment follow-up assessments evaluating self-regulation, adjustment, and stressful life events, substance use and recidivism.

Conditions

Antisocial Behavior

Study Overview

Study Details

Study overview

The goal of this clinical trial is to investigate the effect of two types of cognitive remediation training on real-world behavioral outcomes including substance use, institutional adjustment, and recidivism following release from prison. Each training type is designed to target one of two subtypes of antisocial criminal offenders, who are characterized by either: 1) Attention to context-based deficits, or 2) Affective cognitive control-based deficits. The main questions it aims to answer are: Does matching deficit type with targeted cognitive training improve outcomes (relative to mismatched training)? What are the functional brain mechanisms that underlie treatment change? Participants will: Be assigned to cognitive training that either does or does not match their deficit type. Complete six one-hour sessions of cognitive skills training. Complete pre and post-training behavioral tasks assessing self-regulation deficits. Complete structural MRI scans and functional MRI scans assessing cognitive control. Complete post-treatment follow-up assessments evaluating self-regulation, adjustment, and stressful life events, substance use and recidivism.

Matching Treatments to Cognitive Deficits in Offenders With Substance Use Disorders

Matching Treatments to Cognitive Deficits in Offenders With Substance Use Disorders

Condition
Antisocial Behavior
Intervention / Treatment

-

Contacts and Locations

Albuquerque

Mind Research Network/Lovelace Biomedical Research Institute, Albuquerque, New Mexico, United States, 87106

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Currently incarcerated
  • * No uncorrectable auditory or visual deficits
  • * Able to speak and/or understand English
  • * 5th grade reading level or higher
  • * IQ score = 80 or above
  • * Lifetime history of substance use disorder based on DSM criteria
  • * No history of dementia or other cognitive disability
  • * No indication of current psychotic disorder
  • * No major medical illness or CNS disease
  • * Scores from the Psychopathy Checklist-Revised (PCL-R) meet criteria for one of the designated treatment groups

Ages Eligible for Study

18 Years to 55 Years

Sexes Eligible for Study

MALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

The Mind Research Network,

Study Record Dates

2029-05-31