RECRUITING

Frailty and Muscle Strength Tests in Older Adults Undergoing Major Surgery

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this observational study is to learn if simple tests for frailty and muscle strength can help predict which older adults (age 65 and older) are at higher risk for problems after major abdominal surgery. The main questions it aims to answer are: * Do measures of frailty and muscle strength, taken before surgery, predict complications after surgery? * Can these tests be easily done during a routine pre-surgical visit? Participants will: * Complete brief tests measuring muscle strength, breathing strength, physical function, nutrition status, body composition, and memory during a regular pre-surgical clinic appointment. * Allow researchers to review their medical records 30 and 90 days after surgery to identify any complications or health problems.

Official Title

Feasibility and Correlation of Functional Muscle Strength Tests and Objective Frailty Measures With Clinical Frailty Scale in Patients Undergoing Major Surgery

Quick Facts

Study Start:2025-06-19
Study Completion:2025-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06988176

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Not specified
Standard Ages:OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age 65 years or older.
  2. * Scheduled for elective (planned, non-emergency) major abdominal surgery, including colorectal, hepatobiliary, gynecologic, or urologic procedures.
  3. * Able to attend a routine preoperative evaluation visit.
  4. * Able and willing to complete brief assessments for muscle strength, walking, breathing strength, memory, and nutrition.
  1. * Surgery is an emergency procedure.
  2. * Unable to walk independently (for example, dependent on a wheelchair or bed-bound).
  3. * Significant cognitive impairment that prevents understanding or completing study tests.

Contacts and Locations

Principal Investigator

Monika Nanda, MBBS, MPH, FASA
PRINCIPAL_INVESTIGATOR
University of North Carolina, Chapel Hill

Study Locations (Sites)

University of North Carolina
Chapel Hill, North Carolina, 27599
United States

Collaborators and Investigators

Sponsor: University of North Carolina, Chapel Hill

  • Monika Nanda, MBBS, MPH, FASA, PRINCIPAL_INVESTIGATOR, University of North Carolina, Chapel Hill

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-06-19
Study Completion Date2025-12

Study Record Updates

Study Start Date2025-06-19
Study Completion Date2025-12

Terms related to this study

Keywords Provided by Researchers

  • Frailty
  • sarcopenia
  • elective abdominal surgery
  • Muscle strength
  • Hand Strength
  • Inspiratory muscle strength
  • Post operative complications
  • Risk Assessment
  • Nutrition Assessment
  • Elderly patients
  • Cognitive Function
  • Physical functional performance

Additional Relevant MeSH Terms

  • Frailty
  • Sarcopenia
  • Sarcopenia in Elderly
  • Muscle Strength
  • Post Operative Complications
  • Nutrition Assessment
  • Risk Assessment
  • Elderly (People Aged 65 or More)
  • Hand Strength