RECRUITING

Adenosine vs Diltiazem for Treatment of SVT in the ED

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This is a small, pilot study with a primary goal of assessing patient perceptions of two medication treatments for supraventricular tachycardia in adult patients treated in the Emergency Department.

Official Title

COMparison of Adenosine Versus Diltiazem FOR Supraventricular Tachycardia in the ED (COMFORT-ED) - Pilot Trial

Quick Facts

Study Start:2025-08
Study Completion:2026-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06993038

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 100 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Adult patients (18 years and older)
  2. 2. Diagnosis of acute, stable SVT in the emergency department
  1. 1. Receipt of IV AV-nodal blocking agents prior to study enrollment (includes adenosine, non-dihydropyridine calcium channel blockers, beta-antagonists in pre-hospital and/or hospital setting).
  2. 2. Reported or confirmed personal history of Wolff-Parkinson-White (WPW) syndrome
  3. 3. History of heart failure with reduce ejection fraction (HFrEF) (LVEF\</= 40%)
  4. 4. Severe bronchoconstrictive lung disease
  5. 5. Prior hypersensitivity to study medication
  6. 6. Previously enrolled in pilot study
  7. 7. Pregnant
  8. 8. Incarcerated

Contacts and Locations

Study Contact

Anne Zepeski, PharmD
CONTACT
(319) 356-2577
anne-zepeski@uiowa.edu

Principal Investigator

Anne Zepeski, PharmD
PRINCIPAL_INVESTIGATOR
University of Iowa

Study Locations (Sites)

University of Iowa Health Care
Iowa City, Iowa, 52242
United States

Collaborators and Investigators

Sponsor: Anne E. Zepeski

  • Anne Zepeski, PharmD, PRINCIPAL_INVESTIGATOR, University of Iowa

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-08
Study Completion Date2026-12

Study Record Updates

Study Start Date2025-08
Study Completion Date2026-12

Terms related to this study

Keywords Provided by Researchers

  • diltiazem
  • adenosine
  • emergency medicine

Additional Relevant MeSH Terms

  • Supraventricular Tachycardia (SVT)