RECRUITING

Adenosine vs Diltiazem for Treatment of SVT in the ED

Description

This is a small, pilot study with a primary goal of assessing patient perceptions of two medication treatments for supraventricular tachycardia in adult patients treated in the Emergency Department.

Conditions

Supraventricular Tachycardia (SVT)
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Related Conditions:

Supraventricular Tachycardia (SVT)

Study Overview

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Study Details

Study overview

This is a small, pilot study with a primary goal of assessing patient perceptions of two medication treatments for supraventricular tachycardia in adult patients treated in the Emergency Department.

COMparison of Adenosine Versus Diltiazem FOR Supraventricular Tachycardia in the ED (COMFORT-ED) - Pilot Trial

Adenosine vs Diltiazem for Treatment of SVT in the ED

Condition
Supraventricular Tachycardia (SVT)
Intervention / Treatment

-

Contacts and Locations

Iowa City

University of Iowa Health Care, Iowa City, Iowa, United States, 52242

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Adult patients (18 years and older)
  • 2. Diagnosis of acute, stable SVT in the emergency department
  • 1. Receipt of IV AV-nodal blocking agents prior to study enrollment (includes adenosine, non-dihydropyridine calcium channel blockers, beta-antagonists in pre-hospital and/or hospital setting).
  • 2. Reported or confirmed personal history of Wolff-Parkinson-White (WPW) syndrome
  • 3. History of heart failure with reduce ejection fraction (HFrEF) (LVEF\</= 40%)
  • 4. Severe bronchoconstrictive lung disease
  • 5. Prior hypersensitivity to study medication
  • 6. Previously enrolled in pilot study
  • 7. Pregnant
  • 8. Incarcerated

Ages Eligible for Study

18 Years to 100 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Anne E. Zepeski,

Anne Zepeski, PharmD, PRINCIPAL_INVESTIGATOR, University of Iowa

Study Record Dates

2026-12