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Study of Corneal Biomechanics in Glaucoma Patients Using Brillouin Microscopy

Description

This pilot study evaluates the biomechanical properties of the cornea in glaucoma patients using Brillouin microscopy, a non-contact imaging technique. The study aims to compare corneal stiffness between patients with normal-tension glaucoma, high-tension glaucoma, and healthy controls, and to assess changes in corneal biomechanics following intraocular pressure (IOP)-lowering treatment. The goal is to determine whether Brillouin-derived biomechanical measurements can serve as biomarkers for glaucoma risk and progression.

Conditions

Study Overview

Study Details

Study overview

This pilot study evaluates the biomechanical properties of the cornea in glaucoma patients using Brillouin microscopy, a non-contact imaging technique. The study aims to compare corneal stiffness between patients with normal-tension glaucoma, high-tension glaucoma, and healthy controls, and to assess changes in corneal biomechanics following intraocular pressure (IOP)-lowering treatment. The goal is to determine whether Brillouin-derived biomechanical measurements can serve as biomarkers for glaucoma risk and progression.

Development of Robust Corneal Biomechanical Biomarkers for Glaucoma Using Brillouin Microscopy

Study of Corneal Biomechanics in Glaucoma Patients Using Brillouin Microscopy

Condition
Glaucoma
Intervention / Treatment

-

Contacts and Locations

Baltimore

University of Maryland School of Medicine, Baltimore, Maryland, United States, 21201-1757

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

    Ages Eligible for Study

    18 Years to

    Sexes Eligible for Study

    ALL

    Accepts Healthy Volunteers

    Yes

    Collaborators and Investigators

    University of Maryland, Baltimore,

    Osamah Saeedi, MD, PRINCIPAL_INVESTIGATOR, University of Maryland, Baltimore

    Study Record Dates

    2026-06