RECRUITING

Induction of Labor After Cesarean Using Foley Alone vs. Concurrent Foley and Oxytocin

Description

A randomized trial of patients undergoing a term (≥37 weeks) induction of labor with a history of one prior Cesarean delivery, wherein the provider intends to use a Foley catheter for cervical ripening. The investigators will be comparing Foley alone with concurrent Foley and Oxytocin use at the start of the induction. With this trial, the investigators aim to test our central hypothesis that concurrent Foley and Oxytocin will decrease time to delivery without increasing risks, compared to Foley alone.

Study Overview

Study Details

Study overview

A randomized trial of patients undergoing a term (≥37 weeks) induction of labor with a history of one prior Cesarean delivery, wherein the provider intends to use a Foley catheter for cervical ripening. The investigators will be comparing Foley alone with concurrent Foley and Oxytocin use at the start of the induction. With this trial, the investigators aim to test our central hypothesis that concurrent Foley and Oxytocin will decrease time to delivery without increasing risks, compared to Foley alone.

Labor Induction After Cesarean: A Randomized Trial Of Cervical Balloon With or Without Oxytocin

Induction of Labor After Cesarean Using Foley Alone vs. Concurrent Foley and Oxytocin

Condition
Labor Induction
Intervention / Treatment

-

Contacts and Locations

Philadelphia

Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States, 19146

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Eligible for induction of labor
  • * Live singleton gestation ≥37 weeks
  • * History of 1 cesarean delivery
  • * ≥18 years of age
  • * Cephalic presentation
  • * Intact membranes
  • * English or Spanish speaking (Able to read/understand consent and instructions)
  • * Cervical dilation \<3cm and Bishop score \<8
  • * \>1 prior Cesarean delivery
  • * Known chorioamnionitis
  • * Major fetal anomaly

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Pennsylvania,

Lisa Levine, MD MSCE, PRINCIPAL_INVESTIGATOR, University of Pennsylvania

Study Record Dates

2027-05-01