RECRUITING

A Study of Time-Restricted Eating in Childhood Cancer Survivors

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study will look at whether motivational sessions (including regular calls with a trained health coach) in combination with time-restricted eating (TRE) is an effective way to achieve weight loss and lower cardiometabolic risk in adult survivors of childhood cancer. The researchers will look at how effective this intervention is compared to the usual approach, which is to review educational materials and measure weight once a month. This study will not provide treatment for any disease or cancer.

Official Title

Decreasing Cardiometabolic Risk in Childhood Cancer Survivors: The STRENGTH (Survivors Engaged in Time-Restricted EatiNG After THerapy) Study

Quick Facts

Study Start:2025-05-27
Study Completion:2031-05
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07009288

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Enrolled in the Childhood Cancer Survivor Study (a cohort of 5+ year survivors of childhood cancer diagnosed at age \< 21 between 1970-1999 at 31 participating institutions in North America)
  2. * Previously treated with radiation to the chest, abdomen, or total body
  3. * Are ≥18 years old
  4. * Self-reported body mass index ≥ 25 kg/m2
  5. * Are not pregnant or do not intend to become pregnant in the next year
  6. * Stable weight over the past 6 months (+/- 10 pounds)
  7. * If on oral medication for insulin resistance (ie, metformin), elevated blood pressure, or dyslipidemia, medication dose must be stable (ie, unchanged \> 3 months)
  8. * Have internet access (can be via smartphone or computer). If neither device is available, the study can loan participants a Wi-Fi enabled device.
  1. * Do not reside in the United States
  2. * Do not speak English
  3. * Already fasting \>12 hours per 24-hour day
  4. * On insulin or GLP-1 agonist
  5. * Diagnosis of type 1 diabetes mellitus
  6. * Enrolled in a formal weight management program or other weight loss trial

Contacts and Locations

Study Contact

Danielle Friedman, MD
CONTACT
1-833-MSK-KIDS
friedmad@mskcc.org
Chaya Moskowitz, PhD
CONTACT
646-227-3607

Principal Investigator

Danielle Friedman, MD
PRINCIPAL_INVESTIGATOR
Memorial Sloan Kettering Cancer Center

Study Locations (Sites)

Hunter College
New York, New York, 10065
United States
Memorial Sloan Kettering Cancer Center
New York, New York, 10065
United States
St. Jude Children's Research Hospital (Data Collection Only)
Memphis, Tennessee, 38105
United States
Fred Hutchinson Cancer Research Center (Data Collection Only)
Seattle, Washington, 98109
United States

Collaborators and Investigators

Sponsor: Memorial Sloan Kettering Cancer Center

  • Danielle Friedman, MD, PRINCIPAL_INVESTIGATOR, Memorial Sloan Kettering Cancer Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-05-27
Study Completion Date2031-05

Study Record Updates

Study Start Date2025-05-27
Study Completion Date2031-05

Terms related to this study

Additional Relevant MeSH Terms

  • Childhood Cancer Survivors