RECRUITING

Efficacy of GLP-1 Receptor Agonists in Treating Upper and Lower Extremity Lymphedema

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Lymphedema affects millions and currently lacks effective drug treatments, relying mainly on compression therapy. Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have shown potential in managing obesity and diabetes, which can worsen lymphedema. Although anecdotal evidence suggests benefits of GLP-1 RAs for lymphedema patients, rigorous prospective studies are lacking. This study aims to evaluate the effectiveness of GLP-1 RAs in improving quality of life and clinical outcomes in lymphedema patients, thereby addressing a critical gap in literature and potentially offering a new treatment option.

Official Title

Efficacy of GLP-1 Receptor Agonists in Treating Upper and Lower Extremity Lymphedema

Quick Facts

Study Start:2025-04-09
Study Completion:2027-04-09
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07012642

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Giana Truax
CONTACT
866-266-2577
gtruax@sycamoremm.com
Saba Tasawar
CONTACT
732-741-0970
stasawar@sycamoremm.com

Study Locations (Sites)

River Center
Red Bank, New Jersey, 07701
United States
260 Old Hook Rd Suite 304
Westwood, New Jersey, 07675
United States

Collaborators and Investigators

Sponsor: Advanced Reconstructive Surgery Alliance

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-04-09
Study Completion Date2027-04-09

Study Record Updates

Study Start Date2025-04-09
Study Completion Date2027-04-09

Terms related to this study

Keywords Provided by Researchers

  • Efficacy of GLP-1 in lymphedema

Additional Relevant MeSH Terms

  • Lymphedema