RECRUITING

Kidney Blood Flow During Exercise in Older African American Adults

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this preliminary study is to learn if healthy older African American (AA) adults have a larger change in their kidney blood flow during exercise compared to White (W) adults. The main questions that this study aims to answer are: * Do healthy older AA adults have a larger decrease in kidney blood flow during exercise compared to W adults? * Do healthy older AA adults have a larger decrease in kidney blood flow during other types of stress compared to W adults? During one visit in the research lab, participants will: * Perform cycling exercise while lying down * Undergo a cold hand test * Perform a mental math test Completing this preliminary study will help researchers to understand more about why many AA adults have heart and kidney problems, so future research can study ways to reduce the number of AA adults who have these health issues.

Official Title

Neurovascular Control of Renal Blood Flow During Exercise in Older African American Adults

Quick Facts

Study Start:2024-12-04
Study Completion:2025-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07029165

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:55 Years to 79 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Self-report as either African American or White racial identity
  2. * Born in United States
  3. * Both biological parents identify as same racial identity as participant
  4. * Recreationally active (participating in physical activity for at least 20 minutes per day, at least three times per week, but not training for competitive events)
  5. * Fluent in English
  1. * Hispanic or Latino
  2. * Females who are pregnant or lactating
  3. * Cardiovascular or renal disease
  4. * Hypertension (blood pressure of more than or equal to 130/80 mmHg)
  5. * Diabetes
  6. * Obesity (body mass index of more than or equal to 30 kg/m2)
  7. * Smoker/Tobacco user
  8. * Acute medical conditions
  9. * Taking prescribed cardiovascular, antihypertensive, or renal medications

Contacts and Locations

Study Contact

Rachel C Drew, PhD
CONTACT
617-287-4061
rachel.drew@umb.edu

Principal Investigator

Rachel C Drew, PhD
PRINCIPAL_INVESTIGATOR
University of Massachusetts, Boston

Study Locations (Sites)

University of Massachusetts Boston
Boston, Massachusetts, 02125
United States

Collaborators and Investigators

Sponsor: University of Massachusetts, Boston

  • Rachel C Drew, PhD, PRINCIPAL_INVESTIGATOR, University of Massachusetts, Boston

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-12-04
Study Completion Date2025-12

Study Record Updates

Study Start Date2024-12-04
Study Completion Date2025-12

Terms related to this study

Keywords Provided by Researchers

  • Exercise
  • Cold stress
  • Mental stress

Additional Relevant MeSH Terms

  • Healthy