RECRUITING

An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

A multi-center evaluation of NGM120 in a randomized, double-blind, placebo-controlled study in participants with colorectal cancer who have cancer cachexia.

Official Title

A Phase 2, Multicenter, Randomized, Double Blind, Placebo-controlled Study to Assess the Efficacy, Safety, and Tolerability of NGM120 in Participants With Colorectal Cancer Who Have Cancer Cachexia

Quick Facts

Study Start:2025-06
Study Completion:2027-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07033026

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Documented active diagnosis of colorectal cancer.
  2. 2. Cachexia defined by Fearon criteria of weight loss.
  3. 3. Signed informed consent.
  1. 1. Current active reversible causes of decreased food intake.
  2. 2. Receiving tube feedings or parenteral nutrition at the time of Screening or Randomization.
  3. 3. Have cachexia caused by other reasons.

Contacts and Locations

Study Contact

NGM Study Director
CONTACT
650-243-5555
NGM120CX@ngmbio.com

Principal Investigator

NGM Study Director
STUDY_DIRECTOR
NGM Biopharmaceuticals, Inc

Study Locations (Sites)

NGM Clinical Study Site
Laredo, Texas, 78041
United States

Collaborators and Investigators

Sponsor: NGM Biopharmaceuticals, Inc

  • NGM Study Director, STUDY_DIRECTOR, NGM Biopharmaceuticals, Inc

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-06
Study Completion Date2027-12

Study Record Updates

Study Start Date2025-06
Study Completion Date2027-12

Terms related to this study

Keywords Provided by Researchers

  • Cancer Cachexia
  • Colorectal Cancer
  • CRC

Additional Relevant MeSH Terms

  • Colorectal Cancer
  • CRC (Colorectal Cancer)
  • Cancer Cachexia