RECRUITING

Physical Capacity Building for Chronic Stroke

Description

Cardiac rehabilitation is the standard-of-care treatment option for patients with cardiovascular disease and has been shown to improve many aspects critical to patient recovery. Investigators believe that individuals who have had a stroke need to be treated similarly. Investigators will study the effects of a comprehensive modified cardiac rehabilitation program to determine if it can improve some of the physical and psychosocial problems common in survivors of stroke with and without depression.

Conditions

StrokePost-stroke Depression
Talk to us

Related Conditions:

StrokePost-stroke Depression

Study Overview

On this page

Study Details

Study overview

Cardiac rehabilitation is the standard-of-care treatment option for patients with cardiovascular disease and has been shown to improve many aspects critical to patient recovery. Investigators believe that individuals who have had a stroke need to be treated similarly. Investigators will study the effects of a comprehensive modified cardiac rehabilitation program to determine if it can improve some of the physical and psychosocial problems common in survivors of stroke with and without depression.

Modified Cardiac Rehabilitation to Enhance Post-Stroke Physical and Psychosocial Function: Does Depression Limit the Response?

Physical Capacity Building for Chronic Stroke

Condition
Stroke
Intervention / Treatment

-

Contacts and Locations

Charleston

Medical University of South Carolina, Charleston, South Carolina, United States, 29425

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age 18-70
  • * A diagnosis of stroke at least 6 months prior
  • * Residual paresis in the lower extremity (Fugl-Meyer lower extremity \[LE\] motor score \<34)
  • * Ability to walk without assistance and without an AFO during testing and training at speeds ranging from 0.2-1.0 m/s
  • * Ability to follow instructions, complete cognitive testing and to communicate exertion, pain and distress
  • * No antidepressant medications or no change in doses of psychotropic medication for at least 4 weeks prior to the study (6 weeks if newly initiated medication)
  • * HDRS17 question #3 and PHQ-9 question #9 regarding suicide ≤ 2
  • * Provision of informed consent.
  • * Unable to ambulate at least 150 feet or experienced intermittent claudication while walking
  • * Unstable cardiac arrhythmias, hypertrophic cardiomyopathy, severe aortic stenosis, angina or dyspnea at rest or during ADL's
  • * Dementia
  • * Life expectancy \<1 yr
  • * History of DVT or pulmonary embolism within 6 months
  • * Uncontrolled diabetes with recent weight loss, diabetic coma, or frequent insulin reactions
  • * Severe hypertension with systolic \>200 mmHg and diastolic \>110 mmHg at rest
  • * Attempt of suicide in the last 2 years or suicidal risk assessed by depression screening
  • * Current enrollment in a rehabilitation trial to enhance motor, cognitive and or psychosocial recovery
  • * Severe cognitive impairment (MoCA score ≤15)
  • * Moderate to severe neglect that precludes cognitive testing
  • * Electronic or metallic implants
  • * History of seizures
  • * Women of child bearing potential

Ages Eligible for Study

18 Years to 70 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Medical University of South Carolina,

Ryan Ross, PRINCIPAL_INVESTIGATOR, Medical University of South Carolina

Study Record Dates

2029-08