RECRUITING

Rapamycin and Infection-related Illness

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Conduct a 6-month observational pilot clinical trial to evaluate the safety, monitor the adverse reactions and observe the preliminary effectiveness of medical treatment with oral rapamycin \[Rapamune (Sirolimus)\] in a total of 15 adults, 18 years and older toward preventing and lowering the severity of infectious disease or infection-related illness. Rapamune (Sirolimus) is not approved by the United States Food and Drug Administration (FDA) to prevent and lessen the severity of infection-related illness or infectious disease. Rapamune (Sirolimus) is approved by the FDA for other indications. The main procedures in the study include: * Blood tests to examine cholesterol, lipids, blood platelet counts, inflammation and infection-related health parameters * Questionnaires to examine brain function, mental health, symptoms, overall health status and quality of life * Electrocardiogram (ECG to measure heart function) * Resting diastolic and systolic blood pressure

Official Title

Rapamycin Treatment for Prevention of Infection-related Illness

Quick Facts

Study Start:2025-08
Study Completion:2026-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07054320

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Male or Female Adults, 18 years and older
  2. * Females of child-bearing age taking birth control medication
  3. * Received a Hoskinson Health and Wellness Clinic physician prescription for Rapamune (Sirolimus)
  1. * Adults requiring monoclonal antibody or biological treatment
  2. * Adults diagnosed with an acute lower respiratory or GI infection within 2 weeks
  3. * Adults females who are not taking birth control medication, are pregnant or nursing mothers
  4. * Adults reporting severe mental or physical disability
  5. * Adults reporting unwillingness to travel to onsite clinical facilities
  6. * Adults with any change in chronic disease symptoms or medication within 3 months
  7. * Any contraindications to medical treatment with Rapamune (Sirolimus), as outlined in the FDA-approved medication guide

Contacts and Locations

Study Contact

Julie Weisz
CONTACT
307-387-9850
julie.weisz@hoskinsonhealth.com

Principal Investigator

William Hoskinson, DO
PRINCIPAL_INVESTIGATOR
Hoskinson Health and Wellness Clinic

Study Locations (Sites)

Hoskinson Health and Wellness Clinic
Gillette, Wyoming, 82718
United States

Collaborators and Investigators

Sponsor: Hoskinson Health and Wellness Clinic

  • William Hoskinson, DO, PRINCIPAL_INVESTIGATOR, Hoskinson Health and Wellness Clinic

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-08
Study Completion Date2026-06

Study Record Updates

Study Start Date2025-08
Study Completion Date2026-06

Terms related to this study

Keywords Provided by Researchers

  • Infectious Disease
  • Infection-related illness
  • Rapamycin
  • Rapamune
  • Sirolimus

Additional Relevant MeSH Terms

  • Infectious Diseases