RECRUITING

Quantification & Classification of Inflammatory Cells in Uveitis Using OCT

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this study is to determine if it's possible to use a high resolution imaging device called optical coherence tomography (OCT) to develop an unbiased, standard method of counting and categorizing the various types of cells and proteins found in an eye condition called anterior uveitis. Anterior uveitis is a type of inflammation in the eye that can be caused by many different diseases of the body.

Official Title

Objective Grading of Intraocular Inflammation in Uveitis Using Optical Coherence Tomography

Quick Facts

Study Start:2024-09-01
Study Completion:2026-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07065747

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:5 Years to 85 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Uveitis Group: Eyes with active intraocular inflammation and a clinical diagnose of spondyloarthritis/HLA-B27 associated anterior uveitis, Juvenile Idiopathic Arthritis (JIA) associated chronic anterior uveitis, Herpes Simplex Virus (HSV) anterior uveitis, Birdshot chorioretinitis, Behcet disease uveitis, sarcoidosis associated uveitis, uveitis of any additional type, or uveitis masquerade.
  2. 2. Posterior Vitreous Detachment Group: Eyes with vitreous floaters and posterior vitreous detachment (PVD).
  3. 3. Healthy/Control Group: Healthy eyes with no history of uveitis, PVD, or previous eye surgery.
  1. 1. Inability to give informed consent.
  2. 2. Inability to maintain stable fixation for OCT imaging.
  3. 3. Inability to commit to required visits to complete the study.
  4. 4. Pregnancy and breastfeeding.

Contacts and Locations

Study Contact

Humberto Martinez, COT, MBA
CONTACT
503-494-7712
martinhu@ohsu.edu
Denzil Romfh, OD
CONTACT
503-494-4351
romfhd@ohsu.edu

Principal Investigator

Yan Li, PhD
PRINCIPAL_INVESTIGATOR
Oregon Health and Science University

Study Locations (Sites)

Casey Eye Institute - Oregon Health & Science University
Portland, Oregon, 97239
United States

Collaborators and Investigators

Sponsor: Oregon Health and Science University

  • Yan Li, PhD, PRINCIPAL_INVESTIGATOR, Oregon Health and Science University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-09-01
Study Completion Date2026-12

Study Record Updates

Study Start Date2024-09-01
Study Completion Date2026-12

Terms related to this study

Additional Relevant MeSH Terms

  • Anterior Uveitis (AU)
  • Birdshot Chorioretinitis
  • Behcet Disease
  • Herpes Simplex Virus
  • Juvenile Idiopathic Arthritis (JIA)
  • Spondyloarthritis (SA)
  • Sarcoidosis
  • Posterior Vitreous Detachment