RECRUITING

Mobile Health Intervention to Improve Adherence to Oral Anticancer Therapy

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

New oral anticancer treatments have improved survival across cancer types but introduced challenges in medication adherence and symptom management. The SMART pilot trial will test a new mobile health intervention that facilitates remote adherence and symptom monitoring, patient-provider communication outside of clinic visits regarding the use of oral anticancer treatments, and support for financial and social needs, as well as health literacy support, for 30 English- and Spanish-speaking patients. This study will increase understanding of barriers and facilitators to the use of the proposed mHealth intervention.

Official Title

Mobile Health Intervention to Improve Adherence to Oral Anticancer Therapy: A Pilot Feasibility Clinical Trial

Quick Facts

Study Start:2025-08-26
Study Completion:2026-10
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07073807

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Must speak English or Spanish
  2. * Must be 18 years of age or older
  3. * Have a diagnosis of any type and stage of cancer
  4. * Have a new prescription for an oral anticancer therapy (OAT) initiated within the last 90 days or planned to start within the next 15 days
  5. * Be receiving treatment at UCI Chao Family Comprehensive Cancer Center-affiliated oncology clinics
  6. * Own a smartphone and be willing to receive study-related text messages.
  1. * Have an Eastern Cooperative Oncology Group (ECOG) performance status greater than 2
  2. * Be medically or cognitively unable to give consent or participate in the study
  3. * Be participating in another clinical trial that monitors adherence or symptoms related to the newly prescribed OAT

Contacts and Locations

Study Contact

Gelareh Sadigh, MD
CONTACT
(714) 456-3610
gsadigh@hs.uci.edu
Aarushi Madan, BS
CONTACT

Study Locations (Sites)

Chao Family Comprehensive Cancer Center and Ambulatory Care building
Irvine, California, 92612
United States
UCI Health Cancer Center - Newport
Newport Beach, California, 92627
United States
UCI Health Pacific Breast Care Center
Newport Beach, California, 92627
United States
UCI Health Chao Family Comprehensive Cancer Center
Orange, California, 92868
United States
UCI Health - Yorba Linda
Yorba Linda, California, 92886
United States

Collaborators and Investigators

Sponsor: University of California, Irvine

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-08-26
Study Completion Date2026-10

Study Record Updates

Study Start Date2025-08-26
Study Completion Date2026-10

Terms related to this study

Keywords Provided by Researchers

  • Cancer
  • Oral Anticancer Therapy
  • Medication Adherence
  • Mobile Health
  • Health Literacy
  • Symptom Management
  • Health-Related Social Needs
  • Financial Toxicity
  • adherence
  • symptom burden
  • reminder

Additional Relevant MeSH Terms

  • Cancer
  • Neoplasms