RECRUITING

Reformulated PG324 Ophthalmic Solution for Intraocular Pressure Reduction

Description

This study is designed to see how safe and effective a new eye drop, called Reformulated PG324, is for lowering eye pressure in people with open-angle glaucoma (OAG) or ocular hypertension (OHT).

Conditions

Ocular HypertensionOpen Angle Glaucoma
Talk to us

Related Conditions:

Ocular HypertensionOpen Angle Glaucoma

Study Overview

On this page

Study Details

Study overview

This study is designed to see how safe and effective a new eye drop, called Reformulated PG324, is for lowering eye pressure in people with open-angle glaucoma (OAG) or ocular hypertension (OHT).

A Phase III, Prospective, Double-Masked, Randomized, Multi-Center, Active-Controlled, Parallel Group Comparison Study Assessing the Ocular Hypotensive Efficacy of Reformulated PG324 Ophthalmic Solution in Subjects With Elevated Intraocular Pressure

Reformulated PG324 Ophthalmic Solution for Intraocular Pressure Reduction

Condition
Ocular Hypertension
Intervention / Treatment

-

Contacts and Locations

Dothan

Trinity Research Group, Dothan, Alabama, United States, 36301

Phoenix

Eye Doctors of Arizona, Phoenix, Arizona, United States, 85028

Garden Grove

Orange County Ophthalmology Medical Group, Garden Grove, California, United States, 92843

Inglewood

United Medical Research Institute, Inglewood, California, United States, 90301

Newport Beach

Eye Research Foundation, Newport Beach, California, United States, 92663

Petaluma

North Bay Eye Associates, Petaluma, California, United States, 94954

Sacramento

Sacramento Eye Consultants, Sacramento, California, United States, 95815

DeLand

Central Florida Eye Specialists, DeLand, Florida, United States, 32720

Delray Beach

Glaucoma Specialists of South Florida, Delray Beach, Florida, United States, 33484

Jacksonville

East Coast Institute for Research, LLC, Jacksonville, Florida, United States, 32256

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Diagnosis of open-angle glaucoma or ocular hypertension in both eyes;
  • * Unmedicated intraocular pressure measurements in the study eye as specified in the protocol;
  • * Corrected distance visual acuity equal to or better than 20/100 in the study eye.
  • * Current use of more than 2 ocular hypotensive medications within 30 days;
  • * Intraocular pressure greater than 36 millimeters mercury (mmHg) at Screening;
  • * Use of topical ocular medication of any kind within 5 days of Screening or throughout the study with the exception of ocular hypotensive medications (must be washed out).

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Alcon Research,

Clinical Trial Lead, Pharma, STUDY_DIRECTOR, Alcon Research, LLC

Study Record Dates

2026-05