COMPLETED

The Self-Sampling Pilot Study

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The investigators will test the cytological performance of a nylon-flocked swab at two insertion depths in the anus, 3 cm and 5 cm, to determine which insertion depth is better at collecting cells from the squamocolumnar junction (SCJ), an anatomic site that is particularly vulnerable to carcinogenic transformation. The investigators hypothesize that the 5 cm insertion will result in a higher quality specimen with cells from the SCJ. However, the deeper swab insertion may affect end user acceptability without increasing adequacy or quality.

Official Title

Self-Sampling to Optimize Anal Lesion Outcomes (SOLO) Pilot

Quick Facts

Study Start:2025-07-31
Study Completion:2025-09-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT07085845

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:35 Years
Sexes Eligible for Study:MALE
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Aged ≥ 35 years.
  2. 2. Must be either:
  3. 1. A sexual minority man, or
  4. 2. A woman who has a different identity than the sex she was born with.
  5. 3. Resides in the Milwaukee metropolitan area.
  6. 4. Speak and understand English.
  7. 5. Ability to understand a written informed consent document, and the willingness to sign it.
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Principal Investigator

Alan Nyitray, PhD
PRINCIPAL_INVESTIGATOR
Medical College of Wisconsin

Study Locations (Sites)

Curative Building
Milwaukee, Wisconsin, 53226
United States

Collaborators and Investigators

Sponsor: Medical College of Wisconsin

  • Alan Nyitray, PhD, PRINCIPAL_INVESTIGATOR, Medical College of Wisconsin

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-07-31
Study Completion Date2025-09-12

Study Record Updates

Study Start Date2025-07-31
Study Completion Date2025-09-12

Terms related to this study

Keywords Provided by Researchers

  • squamous cell carcinoma of the anus
  • self-sampling
  • swab performance characteristics

Additional Relevant MeSH Terms

  • Squamous Cell Carcinoma of the Anus