RECRUITING

Gauging Outcomes of Total Milk Ingestion on Lipid and gControl

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Atherosclerotic cardiovascular disease remains the leading cause of death for adults in the United States. The cardiovascular impact of milk consumption remains a matter of long-standing scientific debate. Current guidelines for Americans recommend three daily servings of fat-free or low-fat (1%) dairy over full-fat options due to concerns that saturated fat may increase cardiovascular risk. Yet, the literature does not consistently support non-fat dairy as superior to high-fat dairy for reducing cardiometabolic risk. Identifying the comparative health benefits of non-fat versus high-fat dairy milk would be immediately applicable to patients who seek cardiovascular care. In this randomized, case-crossover trial, the investigators seek to efficiently assess the association between high-fat versus non-fat dairy milk consumption and insulin resistance. Utilizing the Eureka Platform, participants will be randomized to limit their liquid milk consumption to whole milk followed by skim milk (or vice versa), measuring the effect of milk fat content on glycemic index and lipid profile.

Official Title

Gauging Outcomes of Total Milk Ingestion on Lipid and gControl

Quick Facts

Study Start:2025-08
Study Completion:2027-08
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07087184

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Are age ≥18 years
  2. * Have a smartphone
  3. * Are able to use the Eureka mobile application
  4. * Consume, on average, at least one cup of dairy milk daily, at least 5 days per week
  1. * Non-English speaker
  2. * Are lactose intolerant
  3. * History of myocardial infarction
  4. * History of type I or type II diabetes
  5. * Familial hypercholesterolemia
  6. * Plan to change treatment for cholesterol
  7. * Unable to read or sign to provide informed consent

Contacts and Locations

Study Contact

Gregory M Marcus, MD, MAS
CONTACT
415-476-5706
greg.marcus@ucsf.edu
Bella Peña
CONTACT
415-502-3053
bella.pena@ucsf.edu

Principal Investigator

Gregory M Marcus, MD, MAS
PRINCIPAL_INVESTIGATOR
University of California, San Francisco

Study Locations (Sites)

UCSF Medical Center at Parnassus
San Francisco, California, 94143
United States

Collaborators and Investigators

Sponsor: University of California, San Francisco

  • Gregory M Marcus, MD, MAS, PRINCIPAL_INVESTIGATOR, University of California, San Francisco

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-08
Study Completion Date2027-08

Study Record Updates

Study Start Date2025-08
Study Completion Date2027-08

Terms related to this study

Keywords Provided by Researchers

  • Cardiovascular Disease
  • Milk Fat
  • Milk
  • Dairy Products
  • Insulin Resistance
  • Hyperlipidemia

Additional Relevant MeSH Terms

  • Heart Diseases
  • Cardiovascular Disease