RECRUITING

Sleep Apnea Triggers of Atrial Fibrillation: N-of-1 Randomized Control Trial (SPARTA):

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

A pilot N-of-1 randomized controlled trial evaluating the effectiveness of a personalized CPAP intervention in reducing atrial fibrillation (AF) burden and improving AF-related quality of life in patients with moderate to severe obstructive sleep apnea (OSA).

Official Title

Sleep Apnea Triggers of Atrial Fibrillation: N-of-1 Randomized Control Trial (SPARTA):

Quick Facts

Study Start:2025-08-25
Study Completion:2026-05-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07087587

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 85 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Informed consent
  2. 2. Age 18-85 years
  3. 3. High burden paroxysmal AF (≥1%)
  4. 4. Moderate-severe OSA (AHI ≥ 15)
  5. 5. Implanted device with atrial diagnostics
  6. 6. Enrolled in remote monitoring
  1. 1. AF ablation \<6 months
  2. 2. Valvular abnormalities
  3. 3. Excessive daytime sleepiness in safety-critical jobs
  4. 4. Plans for ablation during study
  5. 5. Non-CPAP OSA treatment
  6. 6. Recent device implantation (\<6 months)
  7. 7. Central sleep apnea

Contacts and Locations

Study Contact

Mina Chung, MD
CONTACT
2164442290
CHUNGM@ccf.org
Reena Mehra, MD
CONTACT
216-272-7405
mehrar@medicine.washingon.edu

Study Locations (Sites)

Cleveland Clinic
Cleveland, Ohio, 44195
United States
University of Washington
Seattle, Washington, 98195
United States

Collaborators and Investigators

Sponsor: The Cleveland Clinic

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-08-25
Study Completion Date2026-05-31

Study Record Updates

Study Start Date2025-08-25
Study Completion Date2026-05-31

Terms related to this study

Keywords Provided by Researchers

  • OSA
  • CPAP
  • AFIB

Additional Relevant MeSH Terms

  • Afib
  • Sleep Apnea Syndrome, Obstructive
  • CPAP