RECRUITING

Visual Plasticity Following Brain Lesions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The VIBRANT (Vision Improvement through Behavioral Rehabilitation And Neuroplasticity Training) study is a prospective, double-blind, crossover design (within-subject) in participants with homonymous hemianopia-a type of visual field loss resulting from damage to the post-chiasmatic visual pathways. It aims to investigate whether transcranial random noise stimulation (tRNS) combined with perceptual learning-based training has potential for improving visual impairments.

Official Title

Vision Improvement Through Behavioral Rehabilitation And Neuroplasticity Training

Quick Facts

Study Start:2025-07-17
Study Completion:2028-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07105358

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. At least 18 years of age.
  2. 2. Capable of providing informed consent and complying with study procedures.
  3. 3. Unilateral or bilateral focal brain damage causing loss of vision.
  4. 4. At least three months post-stroke or traumatic brain injury, or a stable brain tumor within the past year.
  1. 1. Severe CNS diseases or disorders unrelated to the focal lesion, which could interfere with study results.
  2. 2. Severe mental health challenges that could interfere with study results, or current or recent (within the past 6 months) drug or alcohol abuse or addiction as defined by DSM-5.
  3. 3. Vision loss resulting from ocular disease or disorder.

Contacts and Locations

Study Contact

Tina Liu, PhD
CONTACT
2027849920
tina.liu@georgetown.edu
Kyungji Moon, MS
CONTACT
2027849949
vpplab@georgetown.edu

Study Locations (Sites)

Georgetown University Medical Center
Washington, District of Columbia, 20057
United States

Collaborators and Investigators

Sponsor: Georgetown University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-07-17
Study Completion Date2028-06-30

Study Record Updates

Study Start Date2025-07-17
Study Completion Date2028-06-30

Terms related to this study

Additional Relevant MeSH Terms

  • Visual Field Defect
  • Stroke
  • Hemianopia
  • Quadrantanopia
  • Cortical Blindness
  • Brain Tumor
  • Traumatic Brain Injury
  • Visual Field Defect, Peripheral