RECRUITING

A Study to Assess Safety and Efficacy of Surgical Implant of RNDP-001 in Patients With Idiopathic Parkinson's Disease

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This clinical trial is designed to test the safety and tolerability of the study intervention, RNDP-001, which will be implanted into the brain of study participants during a surgical procedure.

Official Title

A Phase 1b/2a Study Assessing the Safety and Efficacy of Intraputamenal Dopaminergic Stem Cell Transplants in Patients With Idiopathic Parkinson's Disease

Quick Facts

Study Start:2025-07-17
Study Completion:2031-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07106021

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:45 Years to 75 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Diagnosis of idiopathic Parkinson's disease consistent with the Movement Disorders Society Clinical Criteria
  2. * Age 45 to 75
  3. * Medically stable to undergo a surgical procedure
  1. * Known Parkinson's disease gene mutation or variant
  2. * Previous infusion therapy or surgery for Parkinson's disease
  3. * History of allergic reaction or intolerance to an immunotherapeutic agent
  4. * Contraindication to MRI
  5. * Clinically significant medical conditions likely to interfere with the surgical procedure or study assessments

Contacts and Locations

Study Contact

General Inquiries
CONTACT
<need to obtain>
info@kenaitx.com

Study Locations (Sites)

University of Arizona
Tucson, Arizona, 85721
United States

Collaborators and Investigators

Sponsor: Kenai Therapeutics

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-07-17
Study Completion Date2031-06

Study Record Updates

Study Start Date2025-07-17
Study Completion Date2031-06

Terms related to this study

Keywords Provided by Researchers

  • RNDP-001

Additional Relevant MeSH Terms

  • Idiopathic Parkinson´s Disease
  • Parkinson&#39;s Disease