RECRUITING

A Study to Assess Safety and Efficacy of Surgical Implant of RNDP-001 in Patients With Idiopathic Parkinson's Disease

Description

This clinical trial is designed to test the safety and tolerability of the study intervention, RNDP-001, which will be implanted into the brain of study participants during a surgical procedure.

Study Overview

Study Details

Study overview

This clinical trial is designed to test the safety and tolerability of the study intervention, RNDP-001, which will be implanted into the brain of study participants during a surgical procedure.

A Phase 1b/2a Study Assessing the Safety and Efficacy of Intraputamenal Dopaminergic Stem Cell Transplants in Patients With Idiopathic Parkinson's Disease

A Study to Assess Safety and Efficacy of Surgical Implant of RNDP-001 in Patients With Idiopathic Parkinson's Disease

Condition
Idiopathic Parkinson´s Disease
Intervention / Treatment

-

Contacts and Locations

Tucson

University of Arizona, Tucson, Arizona, United States, 85721

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Diagnosis of idiopathic Parkinson's disease consistent with the Movement Disorders Society Clinical Criteria
  • * Age 45 to 75
  • * Medically stable to undergo a surgical procedure
  • * Known Parkinson's disease gene mutation or variant
  • * Previous infusion therapy or surgery for Parkinson's disease
  • * History of allergic reaction or intolerance to an immunotherapeutic agent
  • * Contraindication to MRI
  • * Clinically significant medical conditions likely to interfere with the surgical procedure or study assessments

Ages Eligible for Study

45 Years to 75 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Kenai Therapeutics,

Study Record Dates

2031-06