RECRUITING

An Observational Study of Individuals With Isolated Dystonia

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Conditions

Isolated/Primary Dystonia That Affects More Than One Region of the BodyDystonia, Isolated Dystonia, Primary Dystonia, Cervical Dystonia

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This is an observational study in individuals with isolated (or primary) dystonia that involves more than one body region. The purpose of the study is to collect detailed information to help your physician and other researchers understand how dystonia impacts your and other patients' lives and how the disease changes over time. The study may also help researchers better understand the clinical scales that are commonly used to evaluate dystonia symptoms and how they affect various areas of life such as well-being, pain, relationships and social interactions, and progress over time. Because this is an observational study, you will not receive any interventional treatment in the study.

Official Title

An Observational Study of Individuals With Isolated Dystonia

Quick Facts

Study Start:2025-06-17
Study Completion:2026-02
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07111663

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:12 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * The participant is willing to sign an informed consent form indicating that he/she understands the purpose of the study; understands and can perform, complete, and comply with all the assessments that are required during the study; and is willing to participate in the study.
  2. * The participant is a male or female between 12 and 65 years of age (inclusive).
  3. * The participant has a clinical diagnosis of isolated (or primary) dystonia for at least one year prior to Visit 1 and meets the study definition of segmental/multifocal or generalized dystonia at Visit 1.
  1. * The participant has a diagnosis of focal dystonia at Visit 1.
  2. * The participant has a diagnosis of dopa-responsive dystonia, secondary dystonia, or psychogenic/functional dystonia.
  3. * The participant has any significant ongoing disease, disorder, laboratory abnormalities, alcohol or illicit drug abuse or dependence, environmental factor, or any ongoing or history of any medical or surgical condition that in the judgment of the investigator, in consultation with the medical monitor and/or sponsor's designee, might jeopardize the participant's safety, impact the scientific objectives of the clinical study, or interfere with participation in the clinical study.
  4. * The participant has a history of any psychiatric or cognitive impairment disorder that, in the opinion of the investigator, may interfere with study conduct.
  5. * The participant has had myotomy or denervation surgery in any affected muscles (e.g., peripheral denervation and/or spinal cord stimulation).
  6. * The participant has marked limitation on passive range of motion that suggests contractures or other structural abnormality (e.g., cervical contractures or cervical spine syndrome).
  7. * The participant has undergone deep brain stimulation (DBS) surgery (even if implant deactivated).

Contacts and Locations

Study Contact

Study Director
CONTACT
617-430-7027
clinicaltrials@vimatx.com

Study Locations (Sites)

Vima Site #004
Scottsdale, Arizona, 85258
United States
Vima Site #010
Aliso Viejo, California, 92656
United States
Vima Site #022
Palo Alto, California, 94301
United States
Vima Site #019
Englewood, Colorado, 80113
United States
Vima Site #003
Boca Raton, Florida, 33486
United States
Vima Site #009
Gainesville, Florida, 32611
United States
Vima Site #008
Miami, Florida, 33176
United States
Vima Site #005
Atlanta, Georgia, 30322
United States
Vima Site #007
Olney, Maryland, 20832
United States
Vima Site #002
Farmington Hills, Michigan, 48334
United States
Vima Site #014
Albuquerque, New Mexico, 87106
United States
Vima Site #017
Commack, New York, 11725
United States
Vima Site #018
New York, New York, 10029
United States
Vima Site #024
New York, New York, 10065
United States
Vima Site #020
Philadelphia, Pennsylvania, 19107
United States
Vima Site #021
Charleston, South Carolina, 29407
United States
Vima Site #016
Memphis, Tennessee, 38157
United States
Vima Site #006
Nashville, Tennessee, 37232
United States
Vima Site #012
Houston, Texas, 77030
United States
Vima Site #011
Richmond, Virginia, 23298
United States
Vima Site #023
Kirkland, Washington, 98034
United States

Collaborators and Investigators

Sponsor: Vima Therapeutics

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-06-17
Study Completion Date2026-02

Study Record Updates

Study Start Date2025-06-17
Study Completion Date2026-02

Terms related to this study

Keywords Provided by Researchers

  • Dystonia, Isolated Dystonia, Primary Dystonia, Cervical Dystonia

Additional Relevant MeSH Terms

  • Isolated/Primary Dystonia That Affects More Than One Region of the Body