RECRUITING

Bromelain for Post-surgery Facial Swelling

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this clinical trial is to learn if Bromelain Supplement works to decrease the amount of swelling or the amount of time swelling is present following jaw surgery. It will also learn about the safety of Bromelain supplement. The main questions it aims to answer are: Does Bromelain decrease facial swelling following orthognathic, or jaw, surgery? Does Bromelain supplement decrease the amount of time that patients are swollen following orthognathic, or jaw, surgery? Participants will: Take Bromelain supplement once daily for 9 days total. Take 2 days before surgery and 7 days following surgery. Keep a log of when the bromelain supplement is taken as well as another other medications. Visit the clinic with pre and post surgical protocol

Official Title

Effectiveness of Bromelain Supplement in Reduction of Facial Swelling Caused by Orthognathic Surgery

Quick Facts

Study Start:2025-09-08
Study Completion:2026-04
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07115212

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * undergoing orthognathic surgery
  1. * craniofacial anomalies
  2. * incomplete patient data
  3. * systemic disease that could affect healing
  4. * allergy to latex or pineapple
  5. * under 18 years of age
  6. * non english speaking

Contacts and Locations

Study Contact

Emma E Palmer, DMD
CONTACT
859-358-6346
emma.palmer@uky.edu

Principal Investigator

Mohamed Bazina, DDS, MSD
PRINCIPAL_INVESTIGATOR
University of Kentucky

Study Locations (Sites)

University of Kentucky
Lexington, Kentucky, 40356
United States

Collaborators and Investigators

Sponsor: Mohamed Bazina

  • Mohamed Bazina, DDS, MSD, PRINCIPAL_INVESTIGATOR, University of Kentucky

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-09-08
Study Completion Date2026-04

Study Record Updates

Study Start Date2025-09-08
Study Completion Date2026-04

Terms related to this study

Keywords Provided by Researchers

  • Bromelain
  • Oral Supplements

Additional Relevant MeSH Terms

  • Malocclusion