RECRUITING

Home Blood Transfusions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This is a pilot single arm study to evaluate the feasibility and acceptability of a home blood transfusion program. Patients will be enrolled with hematologic malignancies and other bone marrow failure syndromes who are transfusion dependent and interested in a home blood transfusion program. Participants enrolled in the study will receive 1-5 units of blood products at home. Data on barriers to administration will be recorded. Surveys and qualitative interviews will be completed to better understand acceptability of the program.

Official Title

A Pilot Study of Home Blood Transfusions for Patient With Cancer Who Have Transfusion Dependent Cytopenias

Quick Facts

Study Start:2025-06-03
Study Completion:2027-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07121140

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Individuals must meet all of the following inclusion criteria in order to be eligible to participate in the study:
  2. * Provide signed and dated informed consent form Willing to comply with all study procedures and be available for the duration of the study
  3. * Male or female, over the age of 18
  4. * Must meet definition of transfusion dependence (require at least 2 blood product transfusions over a 28-day period)
  5. * Receive their cancer care at SKCCC
  6. * Have a history of blood product transfusions and NO history of transfusion reactions,
  7. * Live within a 30-mile range of the Center City SKCCC location.
  8. * Must be willing to allow people into the home
  1. * An individual who meets any of the following criteria will be excluded from participation in this study:
  2. * Patients who have a history of a transfusion reaction
  3. * Heart failure as defined by AHA stage C or NYHA Class II-IV
  4. * Non-English or Spanish speaking
  5. * Are unhoused
  6. * Are incarcerated
  7. * Have poor venous access
  8. * Diagnosis of Solid Tumor malignancy
  9. * Women who are pregnant

Contacts and Locations

Study Contact

Adam Binder, MD
CONTACT
215-955-8874
Adam.Binder@jefferson.edu

Study Locations (Sites)

Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, 19107
United States

Collaborators and Investigators

Sponsor: Thomas Jefferson University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-06-03
Study Completion Date2027-06

Study Record Updates

Study Start Date2025-06-03
Study Completion Date2027-06

Terms related to this study

Keywords Provided by Researchers

  • home blood transfusions
  • blood transfusions
  • RE-AIM
  • Supportive Care

Additional Relevant MeSH Terms

  • Hematologic Malignancy
  • Myelodysplastic Syndromes
  • Acute Myeloid Leukemia
  • Transfusion Dependent Cytopenias