RECRUITING

Lactated Ringer's and Dextrose 5% vs Only Lactated Ringer's in Labor

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this clinical trial is to determine which of two types of standard intravenous (IV) fluids (a combination of 5% dextrose and Lactated Ringers solution and Lactated Ringers solution alone) has a better influence on labor when inducing labor in pregnant women. The main questions it aims to answer are: 1. Does the use of 5% dextrose and Lactated Ringers lead to a shorter labor than the use of just Lactated Ringers? 2. Does the use of 5% dextrose and Lactated Ringers increase the risk of neonatal hypoglycemia when compared to Lactated Ringers? Participants in this trial will be randomly assigned to one of two groups: a group that receives a solution of 5% dextrose and Lactated Ringers, and a group that receives Lactated Ringers alone. Researchers will compare the outcomes of the two groups to see which IV fluid is more effective.

Official Title

Parenteral Lactated Ringer's Plus Dextrose 5% vs Lactated Ringer's in Labor: A Randomized Control Trial on Maternal and Neonatal Outcomes

Quick Facts

Study Start:2025-09
Study Completion:2026-03
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07124130

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Nulliparous women
  2. * Age 18 years or older and able to provide informed consent
  3. * Singleton pregnancy at term
  4. * Induction of labor
  5. * Cephalic presentation
  6. * Unfavorable cervix (Bishop score ≤ 6)
  1. * Age under 18 years
  2. * Involuntarily confined or detained
  3. * Considered as having diminished decision-making capacity
  4. * Spontaneous labor (cervical exam between 5-6 cm) with or without ruptured membraned
  5. * Favorable cervix (Bishop score \>6)
  6. * Diabetes mellitus (both gestational and pre-gestational)
  7. * Structural renal disease
  8. * Acute or chronic kidney disease resulting in abnormal creatinine or proteinuria
  9. * Evidence of chorioamnionitis or non-reassuring fetal testing at the time of enrollment
  10. * Pyrexia (\>38.0 degrees Celsius)
  11. * Stillbirth
  12. * Planned cesarean delivery
  13. * Women presenting with emergent circumstances for labor induction

Contacts and Locations

Study Contact

Tetsuya Kawakita, MD
CONTACT
757-446-7900
kawakit@odu.edu

Study Locations (Sites)

Sentara Norfolk General Hospital
Norfolk, Virginia, 23507
United States

Collaborators and Investigators

Sponsor: Eastern Virginia Medical School

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-09
Study Completion Date2026-03

Study Record Updates

Study Start Date2025-09
Study Completion Date2026-03

Terms related to this study

Keywords Provided by Researchers

  • Induced labor
  • 5% dextrose
  • Lactated Ringers
  • duration of labor

Additional Relevant MeSH Terms

  • Induced Labor