RECRUITING

Lactated Ringer's and Dextrose 5% vs Only Lactated Ringer's in Labor

Description

The goal of this clinical trial is to determine which of two types of standard intravenous (IV) fluids (a combination of 5% dextrose and Lactated Ringers solution and Lactated Ringers solution alone) has a better influence on labor when inducing labor in pregnant women. The main questions it aims to answer are: 1. Does the use of 5% dextrose and Lactated Ringers lead to a shorter labor than the use of just Lactated Ringers? 2. Does the use of 5% dextrose and Lactated Ringers increase the risk of neonatal hypoglycemia when compared to Lactated Ringers? Participants in this trial will be randomly assigned to one of two groups: a group that receives a solution of 5% dextrose and Lactated Ringers, and a group that receives Lactated Ringers alone. Researchers will compare the outcomes of the two groups to see which IV fluid is more effective.

Conditions

Induced Labor
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Related Conditions:

Induced Labor

Study Overview

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Study Details

Study overview

The goal of this clinical trial is to determine which of two types of standard intravenous (IV) fluids (a combination of 5% dextrose and Lactated Ringers solution and Lactated Ringers solution alone) has a better influence on labor when inducing labor in pregnant women. The main questions it aims to answer are: 1. Does the use of 5% dextrose and Lactated Ringers lead to a shorter labor than the use of just Lactated Ringers? 2. Does the use of 5% dextrose and Lactated Ringers increase the risk of neonatal hypoglycemia when compared to Lactated Ringers? Participants in this trial will be randomly assigned to one of two groups: a group that receives a solution of 5% dextrose and Lactated Ringers, and a group that receives Lactated Ringers alone. Researchers will compare the outcomes of the two groups to see which IV fluid is more effective.

Parenteral Lactated Ringer's Plus Dextrose 5% vs Lactated Ringer's in Labor: A Randomized Control Trial on Maternal and Neonatal Outcomes

Lactated Ringer's and Dextrose 5% vs Only Lactated Ringer's in Labor

Condition
Induced Labor
Intervention / Treatment

-

Contacts and Locations

Norfolk

Sentara Norfolk General Hospital, Norfolk, Virginia, United States, 23507

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Nulliparous women
  • * Age 18 years or older and able to provide informed consent
  • * Singleton pregnancy at term
  • * Induction of labor
  • * Cephalic presentation
  • * Unfavorable cervix (Bishop score ≤ 6)
  • * Age under 18 years
  • * Involuntarily confined or detained
  • * Considered as having diminished decision-making capacity
  • * Spontaneous labor (cervical exam between 5-6 cm) with or without ruptured membraned
  • * Favorable cervix (Bishop score \>6)
  • * Diabetes mellitus (both gestational and pre-gestational)
  • * Structural renal disease
  • * Acute or chronic kidney disease resulting in abnormal creatinine or proteinuria
  • * Evidence of chorioamnionitis or non-reassuring fetal testing at the time of enrollment
  • * Pyrexia (\>38.0 degrees Celsius)
  • * Stillbirth
  • * Planned cesarean delivery
  • * Women presenting with emergent circumstances for labor induction

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

Eastern Virginia Medical School,

Study Record Dates

2026-03