RECRUITING

Determining the Effects of Non-invasive Brain Stimulation to Improve Quadriceps Muscle Function After ACL Reconstruction

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

After knee surgery for a torn ACL, many women struggle with weak thigh muscles for years, partly due to reduced brain signals to these muscles. Our research tests a new approach to improve recovery by using low-level brain stimulation to boost these signals. The investigators will study 42 women, aged 18-35, who had ACL surgery. They'll be split into two groups: one receiving real brain stimulation and another getting a placebo, both during thigh-strengthening exercises. Over six sessions, the investigators measure thigh muscle strength, speed, and steadiness, plus two brain signal measures, using special equipment. The investigators will also check if stronger brain signals lead to better muscle performance, especially in women. Our goal is to show that this new method strengthens thigh muscles better than standard rehab, helping women recover better after surgery. If successful, this could improve physical therapy for women recovering from ACL surgery, making daily activities and return to sport easier.

Official Title

Determining the Effects of Non-invasive Brain Stimulation to Improve Quadriceps Muscle Function After ACL Reconstruction.

Quick Facts

Study Start:2025-06-05
Study Completion:2028-06-04
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07128602

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 35 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:No
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. * multiple ligament reconstruction
  2. * osteochondral procedures
  3. * any previous lower extremity surgery
  4. * previous ACL injury
  5. * Metal or implants in the head or neck
  6. * history of neurological disease
  7. * seizures
  8. * severe migraines
  9. * concussion within the last 6 months

Contacts and Locations

Study Contact

Ryan Zarzycki, PhD
CONTACT
215-572-2852
zarzyckir@arcadia.edu

Study Locations (Sites)

Ryan Zarzycki
Glenside, Pennsylvania, 19038
United States

Collaborators and Investigators

Sponsor: Arcadia University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-06-05
Study Completion Date2028-06-04

Study Record Updates

Study Start Date2025-06-05
Study Completion Date2028-06-04

Terms related to this study

Keywords Provided by Researchers

  • acl
  • acl reconstruction
  • corticospinal excitability
  • non-invasive brain stimulation

Additional Relevant MeSH Terms

  • Anterior Cruciate Ligament Reconstruction Rehabilitation
  • Quadriceps Muscle Function