RECRUITING

A Study of Genetic Influence on LDL Hyper-responsiveness in Patients Following a Ketogenic Diet

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to identify whether individuals following a ketogenic diet who experience extreme LDL-C elevation, termed "hyper-responders", have identifiable genetic variations in genes involved in cholesterol absorption.

Official Title

Genetic Influence on LDL Hyper-responsiveness in Patients Following a Ketogenic Diet

Quick Facts

Study Start:2025-10
Study Completion:2027-08
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07137286

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * 18 years of age or older
  2. * LDL-C \>170 mg/dL in response to starting a ketogenic diet
  1. * Patients who do not consent to blood draw for genetic testing
  2. * Those with LDL-C \<170 mg/dL on a ketogenic diet

Contacts and Locations

Study Contact

Saad Omar
CONTACT
507-538-5162
omar.saad@mayo.edu

Principal Investigator

Stephen Kopecky, M.D.
PRINCIPAL_INVESTIGATOR
Mayo Clinic

Study Locations (Sites)

Mayo Clinic
Rochester, Minnesota, 55905
United States

Collaborators and Investigators

Sponsor: Mayo Clinic

  • Stephen Kopecky, M.D., PRINCIPAL_INVESTIGATOR, Mayo Clinic

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-10
Study Completion Date2027-08

Study Record Updates

Study Start Date2025-10
Study Completion Date2027-08

Terms related to this study

Additional Relevant MeSH Terms

  • LDL Hyper-responsiveness