RECRUITING

Memory Support System for Older Chinese Americans With Mild Cognitive Impairment

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The Memory Support System (MSS) from the Healthy Action to Benefit Independence \& Thinking® (HABIT) Program is an evidence-based, non-pharmacological intervention for mild cognitive impairment (MCI). Despite the clinical benefits and feasibility, the MSS was primarily developed and used with non-Hispanic White, English-speaking adults. Racial/ethnic minority groups are chronically under-enrolled in clinical trials for Alzheimer's Disease and Alzheimer's Disease Related Dementias (AD/ADRD) due to lack of linguistically and culturally appropriate adaptation of assessment measures and intervention protocols. The purpose of this research study is to examine whether the MSS from HABIT can help Chinese American older adults with mild thinking and memory problems. Target recruitment is 60 Chinese American adults who are primarily Mandarin- (n=30) and Cantonese-speaking (n=30). Forty participants will participate in the trainer-led day planner training and 20 will participate in self-study of the day planner and receive brain health education. Each participant will also be asked to identify a study partner to participate with them.

Official Title

A Pilot of Memory Support System for Older Chinese Americans With Mild Cognitive Impairment

Quick Facts

Study Start:2025-07-29
Study Completion:2026-05
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07142499

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:55 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * self-identify as Chinese American;
  2. * age 55 and above;
  3. * a diagnosis of MCI as confirmed through documented clinical assessment and/or research-based diagnostic criteria;
  4. * predominantly Cantonese- or Mandarin-speaking;
  5. * able to read and write in Chinese;
  6. * visual and auditory acuity adequate for cognitive testing;
  7. * willing to complete the assessment measures;
  8. * having someone in regular contact to serve as a study partner/informant;
  9. * absence or stable use of prescribed memory-enhancing medications within the last 3 months.
  10. * any significant neurologic disease that would impact their participation and completion of the trial;
  11. * history of psychiatry disorder (DSM 5 criteria) within the last 12 months;
  12. * history of reading or writing disability sufficient to interfere with MSS training; or
  13. * concurrent participation in another relevant clinical trial.
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Clara Li, PhD
CONTACT
212-585-4631
clara.li@mssm.edu
Xinyi Zhang, MA
CONTACT
917-656-4981
xinyi.zhang@mssm.edu

Principal Investigator

Clara Li, PhD
PRINCIPAL_INVESTIGATOR
Icahn School of Medicine at Mount Sinai

Study Locations (Sites)

Li Lab, Icahn School of Medicine at Mount Sinai
New York, New York, 10029
United States

Collaborators and Investigators

Sponsor: Icahn School of Medicine at Mount Sinai

  • Clara Li, PhD, PRINCIPAL_INVESTIGATOR, Icahn School of Medicine at Mount Sinai

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-07-29
Study Completion Date2026-05

Study Record Updates

Study Start Date2025-07-29
Study Completion Date2026-05

Terms related to this study

Additional Relevant MeSH Terms

  • Mild Cognitive Impairment (MCI)