COMPLETED

Microbial Colonization in Three Dimensional (3D) Printed Orthodontic Clear Aligners

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study is being done to compare conventional clear aligners with 3D printed clear aligners to assess if there is any significant difference between the microbial colonization of these appliances. The 3D printed aligner material and conventional aligner materials are being used for investigational purposes and have been approved for their use in fabricating clear aligners for orthodontic tooth movement, but not for the purposes of our study, which is for the fabrication of clear passive aligners to assess microbial colonization.

Official Title

Microbial Colonization in 3D Printed Orthodontic Clear Aligners

Quick Facts

Study Start:2025-09-02
Study Completion:2025-10-17
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT07143370

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Participants are in the permanent dentition
  2. * Participants can understand written English instructions
  3. * Participants have no history of smoking
  4. * Participants will not undergo any active orthodontic treatment.
  1. * Periodontal disease/gingivitis or craniofacial anomalies.
  2. * Severe tooth crowding

Contacts and Locations

Principal Investigator

Aron Aliaga del Castillo, DDS, MS, PhD
PRINCIPAL_INVESTIGATOR
University of Michigan

Study Locations (Sites)

University of Michigan
Ann Arbor, Michigan, 48109
United States

Collaborators and Investigators

Sponsor: University of Michigan

  • Aron Aliaga del Castillo, DDS, MS, PhD, PRINCIPAL_INVESTIGATOR, University of Michigan

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-09-02
Study Completion Date2025-10-17

Study Record Updates

Study Start Date2025-09-02
Study Completion Date2025-10-17

Terms related to this study

Additional Relevant MeSH Terms

  • Orthodontic Aligner
  • Microbial Colonization