RECRUITING

Evaluating the Efficacy of Force Modulating Tissue Bridge Device in Preventing Hypertrophic Scars Following Gender-Affirming Mastectomy

Description

The goal of this randomized, prospective, interventional clinical trial is to evaluate the use of Brijjit® in reducing the incidence of hypertrophic scarring in individuals undergoing gender-affirming bilateral double incision mastectomies at a single-institution, single-surgeon site (Esther A. Kim, MD). Patients will serve as a self-control (one side of the chest receives intervention, the other serves as a control). Primary endpoints include scar appearance and quality. Secondary endpoints include patient perception of the scar using the Patient and Observer Scar Assessment Scale (POSAS). Participants will be taught how to apply Brijjit® at home if any units fall off before 6 weeks postop.

Study Overview

Study Details

Study overview

The goal of this randomized, prospective, interventional clinical trial is to evaluate the use of Brijjit® in reducing the incidence of hypertrophic scarring in individuals undergoing gender-affirming bilateral double incision mastectomies at a single-institution, single-surgeon site (Esther A. Kim, MD). Patients will serve as a self-control (one side of the chest receives intervention, the other serves as a control). Primary endpoints include scar appearance and quality. Secondary endpoints include patient perception of the scar using the Patient and Observer Scar Assessment Scale (POSAS). Participants will be taught how to apply Brijjit® at home if any units fall off before 6 weeks postop.

Evaluating the Efficacy of Force Modulating Tissue Bridge Device in Preventing Hypertrophic Scars Following Gender-Affirming Mastectomy: A Randomized Self-Controlled Trial

Evaluating the Efficacy of Force Modulating Tissue Bridge Device in Preventing Hypertrophic Scars Following Gender-Affirming Mastectomy

Condition
Gender Dysphoria
Intervention / Treatment

-

Contacts and Locations

San Francisco

UCSF Department of Plastic & Reconstructive Surgery, San Francisco, California, United States, 94131

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Age ≥ 19
  • 2. Undergoing double incision gender affirming mastectomy
  • 3. Ability to adhere to Brijjit therapy after surgery
  • 4. Willing to return for follow-up visits and undergo study evaluations
  • 1. History of keloid formation
  • 2. Radiation therapy history
  • 3. Prior surgeries of the chest or breast
  • 4. History or use following prescription medications: 1) accutane within the past year. 2) chronic systemic steroids
  • 5. Active smoker
  • 6. Disorder known to negatively affect wound healing (autoimmune, connective tissue, uncontrolled diabetes)
  • 7. Any other condition determined by PI to preclude subject from joining study

Ages Eligible for Study

19 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of California, San Francisco,

Esther A Kim, MD, PRINCIPAL_INVESTIGATOR, Study Principal Investigator

Study Record Dates

2027-06-01