RECRUITING

Genicular Nerve Block for Knee Pain in the ED

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Patient with atraumatic knee pain without a large knee effusion on x-ray will be randomized to receive either a genicular nerve block (GNB) or standard of care in the emergency department.

Official Title

Ultrasound-Guided Genicular Nerve Block for Knee Pain in the Emergency Department: A Randomized Controlled Trial

Quick Facts

Study Start:2025-07-16
Study Completion:2026-09-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07158736

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Atraumatic knee pain
  2. * \>17 years age
  3. * X-ray of the knee obtained in the ED
  4. * Initial pain score (numeric rating scale) 5-10
  1. * Fracture or dislocation on x-ray
  2. * large knee joint effusion identified on x-ray
  3. * allergy or contraindication to local anesthetics
  4. * History of local anesthetic systemic toxicity after receiving local anesthetics
  5. * Pregnancy
  6. * Incarcerated
  7. * History of knee replacement of affected knee
  8. * Concern for septic joint
  9. * Overlying cellulitis
  10. * Hemodynamic instability
  11. * Altered mental status or inability to consent for procedure.

Contacts and Locations

Study Contact

Umar Clinical Research Coordinator, AB
CONTACT
267-624-4394
umar.aulia@pennmedicine.upenn.edu

Principal Investigator

Michael M Shalaby, MD
PRINCIPAL_INVESTIGATOR
University of Pennsylvania

Study Locations (Sites)

Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, 19104
United States
Pennsylvania Hospital
Philadelphia, Pennsylvania, 19104
United States
Pennsylvania Presbyterian Medical Center
Philadelphia, Pennsylvania, 19104
United States
HUP Cedar
Philadelphia, Pennsylvania, 19143
United States

Collaborators and Investigators

Sponsor: University of Pennsylvania

  • Michael M Shalaby, MD, PRINCIPAL_INVESTIGATOR, University of Pennsylvania

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-07-16
Study Completion Date2026-09-01

Study Record Updates

Study Start Date2025-07-16
Study Completion Date2026-09-01

Terms related to this study

Additional Relevant MeSH Terms

  • Knee Pain