RECRUITING

Genicular Nerve Block for Knee Pain in the ED

Description

Patient with atraumatic knee pain without a large knee effusion on x-ray will be randomized to receive either a genicular nerve block (GNB) or standard of care in the emergency department.

Conditions

Study Overview

Study Details

Study overview

Patient with atraumatic knee pain without a large knee effusion on x-ray will be randomized to receive either a genicular nerve block (GNB) or standard of care in the emergency department.

Ultrasound-Guided Genicular Nerve Block for Knee Pain in the Emergency Department: A Randomized Controlled Trial

Genicular Nerve Block for Knee Pain in the ED

Condition
Knee Pain
Intervention / Treatment

-

Contacts and Locations

Philadelphia

Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States, 19104

Philadelphia

Pennsylvania Hospital, Philadelphia, Pennsylvania, United States, 19104

Philadelphia

Pennsylvania Presbyterian Medical Center, Philadelphia, Pennsylvania, United States, 19104

Philadelphia

HUP Cedar, Philadelphia, Pennsylvania, United States, 19143

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Atraumatic knee pain
  • * \>17 years age
  • * X-ray of the knee obtained in the ED
  • * Initial pain score (numeric rating scale) 5-10
  • * Fracture or dislocation on x-ray
  • * large knee joint effusion identified on x-ray
  • * allergy or contraindication to local anesthetics
  • * History of local anesthetic systemic toxicity after receiving local anesthetics
  • * Pregnancy
  • * Incarcerated
  • * History of knee replacement of affected knee
  • * Concern for septic joint
  • * Overlying cellulitis
  • * Hemodynamic instability
  • * Altered mental status or inability to consent for procedure.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Pennsylvania,

Michael M Shalaby, MD, PRINCIPAL_INVESTIGATOR, University of Pennsylvania

Study Record Dates

2026-09-01