RECRUITING

Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Cancer

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of the study is to determine if an adapted mobile cognitive behavioral therapy (CBT) app (WebMAP Onc) is more effective than standard pain education in reducing chronic pain and improving daily functioning in adolescent survivors of pediatric cancer. This randomized study led by St. Jude Children's Research Hospital will involve 204 participants (102 adolescent survivors and 102 caregivers) across four U.S. hospitals. Outcomes include pain reduction, improved function, and the role of social determinants of health. Assessments occur at baseline, post-treatment, and 3-month follow-up.

Official Title

Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Cancer: A Randomized Clinical Trial

Quick Facts

Study Start:2025-09
Study Completion:2029-02
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07160621

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:10 Years to 17 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. * Adolescent Participants
  2. * 10-17-year-old survivors of childhood cancer or those who received cancer directed therapies (e.g., Langerhan's Histiocytosis)
  3. * At least one-year post treatment completion
  4. * Pain present for 3 months or longer
  5. * Pain interfering with at least one area of daily functioning
  6. * Parent/Caregiver Participants
  7. * ≥ 18 years of age
  8. * Legally authorized to provide informed consent for the adolescent participant
  1. * Adolescent Participants
  2. * Serious comorbid psychiatric condition
  3. * Current substance abuse as determined by the Substance Use Screening Questionnaire
  4. * History of development delay or significant cognitive impairment
  5. * Note: A participant who completed the feasibility study (ADAPTED) cannot participate in the subsequent clinical trial (ADAPTED2)
  6. * Parent/Caregiver Participants
  7. * Not fluent in English or Spanish
  8. * Unable to provide consent for own participation or for the participation of the adolescent participant

Contacts and Locations

Study Contact

Tara Brinkman, PhD
CONTACT
901-595-3300
referralinfo@stjude.org
Tara Brinkman
CONTACT
8662785833
referralinfo@stjude.org

Principal Investigator

Tara Brinkman, PhD
PRINCIPAL_INVESTIGATOR
St. Jude Children's Research Hospital

Study Locations (Sites)

St. Jude Children's Research Hospital
Memphis, Tennessee, 38105
United States

Collaborators and Investigators

Sponsor: St. Jude Children's Research Hospital

  • Tara Brinkman, PhD, PRINCIPAL_INVESTIGATOR, St. Jude Children's Research Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-09
Study Completion Date2029-02

Study Record Updates

Study Start Date2025-09
Study Completion Date2029-02

Terms related to this study

Keywords Provided by Researchers

  • Adult Caregiver
  • Adolescent Survivor

Additional Relevant MeSH Terms

  • Childhood Cancer Survivor
  • Chronic Pain